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100010 - Statement - Consolidated Balance Sheets
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995455 - Disclosure - Nature of Business and Basis of Presentation
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995465 - Disclosure - Summary of Significant Accounting Policies
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995485 - Disclosure - Inventory
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995505 - Disclosure - Fair Value of Financial Instruments
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995525 - Disclosure - Loan and Security Agreement
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995545 - Disclosure - Stockholders' Equity
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995555 - Disclosure - Warrants
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995565 - Disclosure - Net Loss per Common Share
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995585 - Disclosure - License Agreements
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995605 - Disclosure - Income Taxes
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995615 - Disclosure - Related Party Transactions
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995625 - Disclosure - Summary of Significant Accounting Policies (Policies)
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995635 - Disclosure - Accounts Receivable, net (Tables)
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995645 - Disclosure - Inventory (Tables)
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995655 - Disclosure - Intangible Asset (Tables)
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995665 - Disclosure - Fair Value of Financial Instruments (Tables)
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995685 - Disclosure - Loan and Security Agreement (Tables)
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995705 - Disclosure - Stockholders' Equity (Tables)
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995715 - Disclosure - Warrants (Tables)
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995725 - Disclosure - Net Loss per Common Share (Tables)
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995735 - Disclosure - Revenues (Tables)
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995745 - Disclosure - Income Taxes (Tables)
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995755 - Disclosure - Nature of Business and Basis of Presentation - Additional Information (Details)
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995765 - Disclosure - Summary of Significant Accounting Policies - Additional Information (Details)
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995775 - Disclosure - Accounts Receivable, net - Schedule of Accounts Receivable, Net (Details)
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995785 - Disclosure - Accounts receivable, net Additional Information (Details)
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995795 - Disclosure - Inventory - Schedule of Inventory (Details)
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995805 - Disclosure - Inventory - Additional Information (Details)
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995815 - Disclosure - Inventory - Summary of Balance Sheet Classification of Inventory (Details)
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995825 - Disclosure - Intangible Asset - Schedule of Carrying Amount of Intangible Asset (Details)
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995835 - Disclosure - Intangible Asset - Schedule of Finite Lived Intangible Assets Future Amortization Expenses (Details)
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995845 - Disclosure - Fair Value of Financial Instruments - Additional Information (Details)
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995855 - Disclosure - Fair Value of Financial Instruments - Schedule of Fair Value of Financial Instruments Measured on Recurring Basis (Details)
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995865 - Disclosure - Fair Value of Financial Instruments - Schedule of Changes in Fair Value of Contingent Consideration Liabilities (Details)
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995875 - Disclosure - Fair Value of Financial Instruments - Schedule of Fair Value Measurements of Contingent Consideration Recurring Include Significant Unobservable Inputs (Details)
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995885 - Disclosure - Accrued Expenses and Other Current Liabilities - Schedule of Accrued Expenses and Other Current Liabilities (Details)
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995895 - Disclosure - Loan and Security Agreement - Additional Information (Details)
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995905 - Disclosure - Loan and Security Agreement - Schedule of Outstanding Debt and Unamortized Debt Discount Balances (Details)
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995925 - Disclosure - Loan and Security Agreement - Schedule of Principal Payments (Details)
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995935 - Disclosure - Commitments and Contingencies - Additional Information (Details)
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995945 - Disclosure - Commitments and Contingencies - Schedule of Lease Expense (Details)
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995955 - Disclosure - Commitments and Contingencies - Schedule of Future Minimum Lease Payments of Leases (Details)
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995965 - Disclosure - Stockholders' Equity - Additional Information (Details)
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995975 - Disclosure - Stockholders' Equity - Summary of Stock Option Activity (Details)
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995985 - Disclosure - Stockholders' Equity - Schedule of RSU Activity (Details)
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995995 - Disclosure - Stockholders' Equity - Schedule of Stock-Based Compensation Expense Recognized (Details)
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996005 - Disclosure - Warrants - Schedule of Warrant Activity (Details)
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996015 - Disclosure - Warrants - Additional Information (Details)
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996025 - Disclosure - Net Loss per Common Share - Computation of Basic and Diluted Net Loss per Common Share (Details)
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996035 - Disclosure - Net Loss per Common Share - Potentially Dilutive Securities (Details)
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996045 - Disclosure - Revenues - Schedule of Disaggregation of Product Sales (Details)
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996065 - Disclosure - License Agreements - Additional Information (Details)
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996075 - Disclosure - Royalty Agreements - Additional Information (Details)
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996085 - Disclosure - Income Taxes - Schedule of Loss Before Income Taxes and Effective Tax Rates (Details)
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996095 - Disclosure - Income Taxes - Additional Information (Details)
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996105 - Disclosure - Related Party Transactions - Additional Information (Details)
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Statement [Line Items]
Statement [Line Items]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Additional Disclosures [Abstract]
Weighted average contractual term
Warrants
Warrants And Rights Note Disclosure [Text Block]
The entire disclosure for warrants and rights.
Liabilities:
Liabilities, Fair Value Disclosure [Abstract]
Debt Instrument [Axis]
Debt Instrument
Accounts receivable, net
Increase (Decrease) in Accounts Receivable
Plan Name [Domain]
Plan Name
Fair value of issued nonredeemable common stock (or common stock redeemable solely at the option of the issuer). This item includes treasury stock repurchased by the entity. Note: elements for number of nonredeemable common shares, par value and other disclosure concepts are in another section within stockholders' equity.
Common Stock Fair Value
Fair value of common stock
Research and Development, Contract to Perform for Others [Table]
Schedule Of Research And Development Arrangement Contract To Perform For Others [Table]
Schedule of Stockholders' Equity Note, Warrants or Rights [Table Text Block]
Schedule of Warrant Activity
Entity Address, Postal Zip Code
Entity Address, Postal Zip Code
Business Combination
Business Combinations Policy [Policy Text Block]
Share-based compensation arrangement by share-based payment award options forfeitures or canceled in period.
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures Or Canceled in Period
Number of shares, Forfeited/Canceled
Number of shares, Forfeited/Canceled
Fair Value, Recurring and Nonrecurring [Table]
Entity Incorporation, State or Country Code
Entity Incorporation, State or Country Code
Finance Lease, Liability, to be Paid
Total lease payments
Revenues [Abstract]
Interest Paid, Excluding Capitalized Interest, Operating Activities
Interest paid
Provision for income taxes
Increase (Decrease) in Income Taxes
Share-Based Payment Arrangement, Nonvested Award, Excluding Option, Cost Not yet Recognized, Amount
Compensation cost not yet recognized related to unvested RSUs
Number of Operating Segments
Number of operating segments
Finite-Lived Intangible Asset, Expected Amortization, Year Four
2028
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Weighted average exercise price, Exercisable
2022 warrants
Term Loan Two Thousand and Twenty Two Warrants [Member]
Term loan two thousand and twenty two warrants.
Performance obligations
Payment terms
Revenue, Performance Obligation, Description of Payment Terms
Fair Value Hierarchy and NAV [Axis]
Level 2
Fair Value, Inputs, Level 2 [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Lessee, Operating Lease, Description
Lessee, operating lease, description
Number of customers
Number Of Customers
Number of customers.
Long-Term Debt, Type [Domain]
Long term DebtType
Stock-based compensation expense capitalized
Share-Based Payment Arrangement, Amount Capitalized
Long-Term Debt, Maturity, Year Five
2028
Prepayment Occurs Prior to February 1, 2024
Debt Instrument Prepayment Occurring Prior to February One Two Thousand Twenty Four [Member]
Debt instrument prepayment occurring prior to february one two thousand twenty four.
Lessee, Operating Lease, Liability, to be Paid, Remainder of Fiscal Year
2024
Commitments and Contingencies Disclosure [Text Block]
Commitments and Contingencies
The authorized amount under a common stock sales agreement.
Common Stock Sales Agreement Authorized Amount
Common stock sales agreement, authorized amount
Total
Inventory Current and Noncurrent
Inventory current and noncurrent.
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block]
Schedule of changes in fair value of contingent consideration liabilities
Product and Service [Axis]
Product and Service
Lender Name [Axis]
Lender Name
Investment, Name [Domain]
Investment, Name
Adjustments, Noncash Items, to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract]
Adjustments to reconcile net loss to net cash used in operating activities:
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Collaborative Arrangement and Arrangement Other than Collaborative
Debt instruments maturity, month and year.
Debt Instruments Maturity Month And Year
Debt instrument maturity, month and year
2020 warrants
Represents about term loan tranche one.
Term Loan2020 Tranche One [Member]
Term loan 2020 tranche one
Employee Stock [Member]
Employee Stock Purchase Plan
ESPP
Related Party Transaction [Line Items]
Concentration Risk Benchmark [Axis]
Equity [Text Block]
Stockholders' Equity
Revenues
Revenue from Contract with Customer [Text Block]
Contract with Customer, Liability [Abstract]
Sale of Stock [Domain]
Sale of Stock
Long-Term Debt, Gross
Total Outstanding Debt
Total principal payments outstanding
Remaining Weighted-Average Useful Life
Intangible assets, Estimated period of benefit
Finite-Lived Intangible Asset, Useful Life
Inventory, Policy [Policy Text Block]
Inventory
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Abstract]
Schedule of Inventory, Noncurrent [Table Text Block]
Summary of Balance Sheet Classification of Inventory
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Entity Central Index Key
Entity Central Index Key
Leerink.
Leerink [Member]
Leerink
Trade Receivables
Trade Receivables.
Trade receivables
Represents the number of late-stage candidates included in the Company's product candidate portfolio.
Number Of Late Stage Product Candidates
Number of late-stage candidates not yet approved in Company's product candidate portfolio
Cash Equivalents, at Carrying Value
Cash Equivalents
Cash Equivalents, at Carrying Value, Total
Warrant [Member]
Warrants
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period
Number of shares, Forfeited/Canceled
Increase (Decrease) in Operating Capital [Abstract]
Changes in operating assets and liabilities:
Advertising costs
Advertising Expense
Common Stock, Shares, Issued
Balance (in shares)
Balance (in shares)
Common stock, shares issued
Number of common shares
Common Stock, Shares, Issued, Total
Prepayment Occurs On or After February 1, 2024 but Prior to February 1, 2025
Debt Instrument Prepayment Occurring On or After February One Two Thousand Twenty Four But Prior to February One Two Thousand Twenty Five [Member]
Debt instrument prepayment occurring on or after february one two thousand twenty four but prior to february one two thousand twenty five.
Fair value of warrant liability.
Fair Value Of Warrant Liability
Warrant liability
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table]
Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table]
Fair Value Measurement Inputs and Valuation Techniques [Table]
Revenue Discount rate
Measurement Input, Revenue Multiple [Member]
Long-Term Debt, Maturity, Year Four
2027
Tranche Two Sub Tranche One
Tranche two sub tranche one.
Tranche Two Sub Tranche One [Member]
Income Statement [Abstract]
Entity Address, State or Province
Entity Address, State or Province
The final payment fee at extinguishment of debt.
Extinguishment Of Debt Fee Amount
Final payment fee
Issuance of common stock upon exercise of options and under employee stock purchase plan
Stock Issued During Period, Value, Employee Stock Purchase Plan
Finance Lease, Liability, to be Paid, Year One
2025
Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest
Loss before income taxes
Loss before income taxes
Class of Warrant or Right [Table]
Contingent consideration
Contingent Consideration [Member]
Contingent consideration [Member].
Third Amendment To Loan and Security Agreement
Third Amendment To Loan and Security Agreement [Member]
Third amendment to loan and security agreement.
The amount of future payments payable under the collaboration arrangement.
Collaboration Arrangement Future Potential Payments
Future milestone payments
The minimum amount of market capital to be maintained under debt instruments.
Long Term Debt Additional Drawn Covenant Minimum Market Capitalization Amount
Minimum amount of market capital to be maintained
Sharebased compensation arrangement by sharebased payment award other than option lapsed intrinsic value.
Sharebased Compensation Arrangement by Sharebased Payment Award Other than Option Lapsed Intrinsic Value
Intrinsic value lapsed
Concentration Risk Type [Domain]
Loss Contingencies [Table]
Loss Contingencies [Table]
Customer [Axis]
'Customer Concentration Risk
Customer Concentration Risk [Member]
Finite-Lived Intangible Asset, Expected Amortization, Year Three
2027
Liability Class [Axis]
Minimum different from remaining percentage of cash flow
Long Term Debt Different From Remaining Drawn Covenant Minimum Cash Flow Percentage
Long term debt different from remaining drawn covenant minimum cash flow percentage.
Raw materials
Inventory, Raw Materials, Gross
Payment of debt issuance costs
Payments of Debt Issuance Costs
Amortization of final payment fee
Amortization of Debt Issuance Costs
Amortization of debt issuance costs
Cover [Abstract]
Net loss per common share, basic
Earnings Per Share, Basic
Earnings Per Share, Basic, Total
Fourth amendment to loan and security agreement.
Fourth Amendment To Loan and Security Agreement [Member]
Fourth Amendment To Loan and Security Agreement
Lessee, Operating Lease, Option to Extend
Lessee, operating lease, option to extend
The fair value of outstanding warrants.
Fair Value Of Warrants
Fair value
Operating expenses:
Operating Expenses [Abstract]
Term Loan Advances Other Than Tranche 1A
Term Loan Advances Other Than Tranche One A [Member]
Term loan advances other than tranche one A.
Revenue milestones.
Revenue Milestones
Revenue milestones
Finance Lease, Principal Payments
Payments on principal portion of finance lease obligation
Represents the prepayment of debt occurring prior to first anniversary of closing date.
Debt Instrument Prepayment Occurring Prior To First Anniversary Of Closing Date [Member]
Prepayment Occurs Prior to First Anniversary of Closing Date
License Revenue
License Fee
License [Member]
Represents information pertaining to AXS-02.
Axs02 [Member]
AXS-02
Share-Based Payment Arrangement, Expense
Stock-based compensation expense
Expense
Advertising Costs
Advertising Cost [Policy Text Block]
Finance Lease, Weighted Average Discount Rate, Percent
Weighted average discount rate
Intangible Assets [Abstract]
Intangible Assets Abstract.
Loss in fair value of contingent consideration
Change in fair value of contingent consideration
Change In Fair Value Of Contingent Considerations
Change in fair value of contingent considerations.
Adjustment to fair value
Retained Earnings (Accumulated Deficit)
Accumulated deficit
Accumulated deficit
Retained Earnings (Accumulated Deficit), Total
Retained Earnings (Accumulated Deficit), Beginning Balance
Retained Earnings (Accumulated Deficit), Ending Balance
Schedule of future minimum lease payments.
Schedule of Future Minimum Lease Payments [Table Text Block]
Schedule of Future Minimum Lease Payments of Leases
Plan Name [Axis]
Plan Name
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Number of shares, Outstanding, ending balance
Number of shares, Outstanding, beginning balance
Assets, Current [Abstract]
Current assets:
Tranche three sub tranche one.
Tranche Three Sub Tranche One [Member]
Tranche Three Sub Tranche One
United States
UNITED STATES
Weighted average price at which warrants were issued.
Warrants Issued In Period Weighted Average Exercise Price
Issued
Prior period adjustments for product sales resulting from changes in estimates
Prior Period Adjustments For Product Sales Resulting From Changes in Estimates
Prior period adjustments for product sales resulting from changes in estimates.
Net Cash Provided by (Used in) Operating Activities
Net cash used in operating activities
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value
Weighted average grant date fair value, Forfeited
Royalty Expense
Milestone payments or royalties
Royalty expense
Product and Service [Domain]
Product and Service
Lessee, Operating Lease, Term of Contract
Operating lease, lease term
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Outstanding, Weighted Average Remaining Contractual Terms
Weighted average contractual term
Sunosi and Auvelity.
Sunosi and Auvelity [Member]
Sunosi and Auvelity
Property, Plant and Equipment, Net
Equipment, net
Property, Plant and Equipment, Net, Total
Property, Plant and Equipment, Net, Beginning Balance
Property, Plant and Equipment, Net, Ending Balance
Lessee, Operating Lease, Liability, to be Paid, Year Four
2028
Net Cash Provided by (Used in) Operating Activities [Abstract]
Cash flows from operating activities
Fair Value, Recurring [Member]
Schedule of fair value of financial instruments measured on a recurring basis
Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block]
Common Stock, Par or Stated Value Per Share
Common stock, par value
Accrued royalties
Accrued Royalties, Current
Accounts Payable and Other Accrued Liabilities, Current
Accrued expenses and other current liabilities
Total
Stock Options
Operating Lease, Right-of-Use Asset, Statement of Financial Position [Extensible Enumeration]
Intangible Asset
Intangible Assets Disclosure [Text Block]
Measurement Input Type [Domain]
Taxes Payable, Current, Total
Taxes Payable, Current
Accrued taxes
Accounts Receivable, net
Accounts Receivable [Policy Text Block]
Statement of Cash Flows [Abstract]
Counterparty Name [Axis]
Counterparty Name
Underwriting discounts and commissions.
Underwriting Discounts And Commissions
Underwriting discounts and commissions
Antidilutive Securities, Name [Domain]
Antidilutive Securities, Name
Accounts, Notes, Loans and Financing Receivable [Line Items]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights
Common stock to be issued if warrants are exercised (in shares)
Finance lease liability recognized in exchange of right of use asset.
Finance Lease Liability Recognized in Exchange of Right of Use Asset
Finance lease liability recognized during period
Fifth Amendment To Loan And Security Agreement
Fifth Amendment To Loan And Security Agreement [Member]
Fifth amendment to loan and security agreement member.
Equity Components [Axis]
Equity Components
Entity Address, Address Line One
Entity Address, Address Line One
Other offering costs.
Other Offering Costs
Other offering costs
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
Computation of Basic and Diluted Net Loss per Common Share
Employee-related Liabilities, Current
Accrued compensation
Employee-related Liabilities, Current, Total
Related Party Transaction [Table]
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period
Number of shares, Granted
Valuation Approach and Technique [Axis]
The commission percentage paid under a common stock sales agreement.
Common Stock Sales Agreement Commission Percentage
Common stock sales agreement, commission percentage
The entire disclosure for license agreements.
License Agreements Disclosure [Text Block]
License Agreements
Contingent consideration, measurement input
Business Combination, Contingent Consideration, Liability, Measurement Input
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Schedule of Potentially Dilutive Securities
Line of Credit Facility, Maximum Borrowing Capacity
Maximum loan amount
Share based compensation arrangement by share based payment award options expired in period.
Share Based Compensation Arrangement By Share Based Payment Award Options Expired In Period
Number of shares, Expired
Outside of the United States
Non-US [Member]
Ex-U.S. Market Sales
Probability weighted income approach
Valuation, Income Approach [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number
Number of shares, Outstanding, ending balance
Number of shares, Outstanding, beginning balance
Finite-Lived Intangible Asset, Expected Amortization, Year Two
2026
Amendment Flag
Amendment Flag
Represents the number of financial institutions holding the Company's cash.
Number Of Financial Institutions Holding Deposits
Number of financial institutions that hold the Company's cash
Issuance of common stock upon financing
Stock Issued During Period Value Financing
Value of stock issued pursuant to a financing arrangement during the period.
Operating Lease, Liability, Noncurrent
Operating lease liability, long-term
Debt Instrument, Name [Domain]
Debt Instrument, Name
Additional Paid in Capital, Common Stock
Additional paid-in capital
Additional Paid in Capital, Common Stock, Beginning Balance
Additional Paid in Capital, Common Stock, Ending Balance
Information pertaining to Pfizer, Inc.
Pfizer Inc [Member]
Pfizer Inc
Number of Asian markets.
Number of Asian Markets
Number of Asian markets
Accounts Receivable, net
Receivables [Abstract]
Net loss
Net loss
Lessee, Lease, Description [Table]
Inventory, Noncurrent, Total
Inventory, Noncurrent
Non-current inventory and other assets
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period
Issuance of common stock upon exercise of options (in shares)
Number of shares, Exercised
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number
Number of shares, Exercisable
Variable Rate [Domain]
Variable Rate
Research and Development Expense [Member]
Research and Development
Mark Jacobson
Mark Jacobson [Member]
Mark Jacobson.
Customer [Domain]
Product Sales
Product Sales Member
Product Sales Member
Equity Component [Domain]
Equity Component
Statistical Measurement [Domain]
Statistical Measurement
Rule 10b5-1 Trading Plan One
Rule 10b5-1 Trading Plan One [Member]
Rule 10b5-1 Trading Plan One
Contingent consideration liability, non-current
Contingent consideration, non-current
Business Combination, Contingent Consideration, Liability, Noncurrent
Increase (Decrease) in Other Accounts Payable and Accrued Liabilities
Accrued expenses and other current liabilities
Disaggregation of Revenue [Table]
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest
Net loss
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total
Preferred Stock, Shares Issued
Preferred stock, shares issued
Preferred Stock, Shares Issued, Total
Cost of revenue (excluding amortization and depreciation)
Cost of product sales (excluding amortization and depreciation)
Cost of Goods and Service, Excluding Depreciation, Depletion, and Amortization
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Nonvested, Number of Shares
Non-vested options outstanding
Share-based Compensation Arrangement by Share-based Payment Award, Options, Nonvested, Number of Shares, Beginning Balance
Share-based Compensation Arrangement by Share-based Payment Award, Options, Nonvested, Number of Shares, Ending Balance
Carrying value as of the balance sheet date of obligations incurred through that date and payable for research and development. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).
Accrued Research And Development Current
Accrued research and development
Issuance of common stock upon exercise of options and under employee stock purchase plan (in shares)
Stock Issued During Period, Shares, Employee Stock Purchase Plans
Accrued royalty payments
Accrued Royalties
Prepaid Expense and Other Assets, Current
Prepaid and other current assets
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Weighted average exercise price, Forfeited
License Agreements
License Agreements [Policy Text Block]
License Agreements.
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Collaborative Arrangement and Arrangement Other than Collaborative
Auvelity
Auvelity [Member]
Auvelity.
Schedule of Finite-Lived Intangible Assets [Table Text Block]
Schedule of Carrying Amount of Intangible Asset
Common Stock, Shares, Outstanding
Common stock, shares outstanding
Common Stock, Shares, Outstanding, Beginning Balance
Common Stock, Shares, Outstanding, Ending Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward]
Number of shares
Fair Value Measurements
Fair Value Measurement, Policy [Policy Text Block]
Contingent Consideration by Type [Axis]
Probability of Occurrence (periodic for each Milestone)
Probability Of Occurrence Periodic For Each Milestone [Member]
Probability of occurrence periodic for each milestone [Member]
Preferred Stock, Par or Stated Value Per Share
Preferred stock, par value
Antidilutive Securities [Axis]
Antidilutive Securities
Cash
Non-current inventory and other assets
Non Current Inventory and Other Assets
Non-current inventory and other assets
Entity Interactive Data Current
Entity Interactive Data Current
Product Sales
Product [Member]
Customer Two
Customer Two [Member]
Customer Two.
Accounting policies.
Accounting Policies [Table]
Accounting Policies [Table]
Represents the information if the outstanding principle and advances under loan agreement exceeds fifty five million.
Outstanding Advances Under Loan Agreement Equals Or Exceeds Sixty Five Million [Member]
Outstanding principle and advances under the loans agreement exceeds 65 million
Document Quarterly Report
Document Quarterly Report
Royalty revenue
Royalty Revenue
Royalty Revenue
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value
Weighted average grant date fair value, Vested
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Total
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents
Cash at beginning of period
Cash at end of period
License Agreements
License Agreement Terms [Member]
License Agreement
Related Party Transactions Disclosure [Text Block]
Related Party Transactions
Finance Lease, Liability, Undiscounted Excess Amount
Less imputed interest
Statistical Measurement [Axis]
Statistical Measurement
Contingent Consideration
Commitments and Contingencies, Policy [Policy Text Block]
Operating Lease, Cost
Total operating lease expense
Related and Nonrelated Parties [Domain]
Related Party
Development milestones.
Development Milestones
Development milestones
Schedule of Disaggregation of Product Sales
Disaggregation of Revenue [Table Text Block]
Probability of occurrence (cumulative through each Milestone)
Probability Of Occurrence Cumulative Through Each Milestone [Member]
Probability of occurrence cumulative through each milestone [Member].
Finite-Lived Intangible Assets, Gross, Total
Finite-Lived Intangible Assets, Gross
Gross carrying amount
Share-Based Payment Arrangement, Restricted Stock and Restricted Stock Unit, Activity [Table Text Block]
Schedule of RSU Activity
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant
Shares available for future grant
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value
Weighted average grant date fair value, Granted
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Expected vesting period for non-vested share-based compensation
Number of warrants (or share units) exercised during the current period.
Warrants Exercised In Period
Exercised
The increase (decrease) during the reporting period in the value of prepaid expenses and other current assets not separately disclosed in the statement of cash flows, for example, deferred expenses, intangible assets, or income taxes.
Increase Decrease In Prepaid Expense And Other Assets Current
Prepaid expenses and other current assets
2023 Warrants
Term Loan Two Thousand and Twenty Three Warrants [Member]
Term Loan Two Thousand and Twenty Three Warrants [Member]
Research and Development Expense, Policy [Policy Text Block]
Research and Development Costs
Statement of Income Location, Balance [Axis]
Income Statement Location
Accounting policies.
Accounting Policies [Line Items]
Accounting Policies [Line Items]
Assets
Total assets
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Settlements
Payments
Proceeds from Long-Term Lines of Credit
Proceeds from draw down of debt
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period
Number of shares, Vested
Represents information pertaining to the 2015 Equity Compensation Plan.
Two Thousand Fifteen Equity Compensation Plan [Member]
2015 Plan
AXS-05.
Represents information pertaining to AXS-05.
Axs05 [Member]
AXS-05
New Accounting Pronouncements, Policy [Policy Text Block]
Recent Accounting Pronouncements
Entity Address, City or Town
Entity Address, City or Town
Equity [Abstract]
Beneficial ownership percentage
Beneficial Ownership Percentage
Beneficial ownership percentage.
Assets:
Assets, Fair Value Disclosure [Abstract]
Cash paid for common stock issuance costs
Cash paid for common stock issuance costs
Payments of Stock Issuance Costs
Tranche three sub tranche two.
Tranche Three Sub Tranche Two [Member]
Tranche Three Sub Tranche Two
Effective Income Tax Rate Reconciliation, Percent [Abstract]
Income Taxes
Schedule of Maturities of Long-Term Debt [Table Text Block]
Schedule of Principal Payments
December two thousand nineteen sales agreement.
December Two Thousand Nineteen Sales Agreement [Member]
December 2019 Sales Agreement
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period
Number of shares, Forfeited
Finance Lease, Liability, to be Paid, Year Two
2026
Jazz pharmaceuticals Plc.
Jazz Pharmaceuticals Plc [Member]
Jazz Pharmaceuticals Plc
Royalty Agreements
Royalty Agreements Disclosure [Text Block]
Royalty agreements disclosure text block
Depreciation
Depreciation
Depreciation, Total
Share Price
Share Price
Share price
Non-refundable upfront payment received
upfront payment received
upfront payment received
Fair value price of a single share of a number of saleable stocks of a company
Share Price Fair Value
Fair value share price
Operating Lease, Weighted Average Discount Rate, Percent
Operating lease, discount rate
Fair Value Disclosures [Abstract]
Finance Lease, Liability, to be Paid, Fiscal Year Maturity [Abstract]
Finance Lease
Stock Issued During Period, Value, New Issues
Proceeds from issuance of common stock, gross
Chief Executive Officer [Member]
Dr. Tabuteau
Net equity impact of the value of new stock issued during the period. Includes shares issued in an initial public offering or a secondary public offering.
Stock Issued During Period Value New Issues Net
Proceeds from issuance of common stock, net
Stock Issued During Period, Value, Stock Options Exercised
Issuance of common stock upon exercise of options
Lessee, Lease, Description [Line Items]
Liabilities, Current [Abstract]
Current liabilities:
Stock vested during period value restricted common stock award.
Stock Vested During Period Value Restricted Common Stock Award
Issuance of common stock upon vesting of RSUs
Accounts Receivable
Accounts Receivable [Member]
Tranche Two Sub Tranche Two
Tranche two sub tranche two.
Tranche Two Sub Tranche Two [Member]
Document Type
Document Type
Title of 12(b) Security
Title of 12(b) Security
Cash and Cash Equivalents, at Carrying Value
Cash and cash equivalents
Cash and Cash Equivalents, at Carrying Value, Total
Cash and Cash Equivalents, at Carrying Value, Beginning Balance
Cash and Cash Equivalents, at Carrying Value, Ending Balance
Lease, Cost [Table Text Block]
Schedule of Lease Expense
Statement of Stockholders' Equity [Abstract]
Fair value of contingent consideration
Beginning Balance
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability Value
Ending Balance (Level 3)
Document Fiscal Period Focus
Document Fiscal Period Focus
Research and Development Expense
Research and development
Research and development expense recognized
Research and Development Expense, Total
Payment, Tax Withholding, Share-Based Payment Arrangement
Payments of tax withholdings on stock award
Long-Term Debt, Excluding Current Maturities
Loan payable, long-term
Loan payable, long-term
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Number of shares, Granted
Revenue Recognition
Disaggregation of Revenue [Abstract]
Asset Class [Domain]
Accounts Receivable, net
Loans, Notes, Trade and Other Receivables Disclosure [Text Block]
Finance Lease, Right-of-Use Asset, after Accumulated Amortization, Total
Finance Lease, Right-of-Use Asset, after Accumulated Amortization
Finance lease, right-of-use asset
Other development and sales based milestones recognized.
Other Development and Sales based Milestones Recognized
Other development and sales based milestones recognized
Lessee, Leases [Policy Text Block]
Leases
Forty five day period after closing of fourth amendment to loan and security agreement.
Forty Five Day Period After Closing Of Fourth Amendment To Loan And Security Agreement [Member]
45-day Period after Closing of Fourth Amendment to Loan and Security Agreement
The final payment fee to be paid under the debt arrangement as a percentage of aggregate amount of all term loan advances minus the aggregate amount of repayments made.
Debt Instrument Final Payment Fee Threshold Percentage Of Debt Outstanding
Percentage of final payment fee
The minimum percentage of revenue should be achieved under the debt instrument.
Long Term Debt Additional Drawn Minimum Revenue Percent
Minimum product revenue percent
Warrants Issued With Debt Financing
Warrants issued with debt financing.
Issuance of warrants in connection with debt financing
Thereafter
Long-Term Debt, Maturity, after Year Five
Prepayment Occurs On or After February 1, 2025 but Prior to February 1, 2026
Debt Instrument Prepayment Occurring On or After February One Two Thousand Twenty Five But Prior to February One Two Thousand Twenty Six [Member]
Debt instrument prepayment occurring on or after february one two thousand twenty five but prior to february one two thousand twenty six.
Class of Warrant or Right, Exercise Price of Warrants or Rights
Weighted average exercise price, Ending balance
Weighted average exercise price, Beginning balance
Exercise price of warrants (in dollars per share)
Interest expense, net
Investment Income, Net
Investment Income, Net, Total
Class of Warrant or Right [Line Items]
Sale of Stock [Axis]
Sale of Stock
Net Cash Provided by (Used in) Investing Activities [Abstract]
Cash flows from investing activities
Finite lived intangible assets amortization expense after year four.
Finite Lived Intangible Assets Amortization Expense After Year Four
Thereafter
Less: Reserves for Variable Consideration
Reserves for Variable Consideration
Reserves for Variable Consideration.
Less: Reserves for variable consideration
Total product sales, net
Revenue from Contract with Customer, Excluding Assessed Tax, Total
Revenue
Revenue from Contract with Customer, Excluding Assessed Tax
Income Taxes
Income Tax Disclosure [Text Block]
Lessee, Finance Lease, Renewal Term
Finance lease, renewal term
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
Schedule Of Loss Before Income Taxes Effective Income Tax Rate
Schedule of Loss Before Income Taxes and Effective Tax Rates
Finance lease, liability, to be paid, after year four.
Finance Lease, Liability, to Be Paid, After Year Four
Thereafter
Warrants and Rights Note Disclosure [Abstract]
WarrantsAndRightsNoteDisclosureAbstract
Tranches expire undrawn
Undrawn Expire Tranches
Undrawn expire tranches.
Line of Credit Facility [Line Items]
Line Of Credit Facility [Line Items]
Selling, general and administrative
Selling, General and Administrative Expense
Selling, General and Administrative Expense, Total
Total
Finite-Lived Intangible Assets, Net
Finite-Lived Intangible Assets, Net, Ending Balance
Finite-Lived Intangible Assets, Net, Beginning Balance
Stock vested during period shares restricted common stock award.
Stock Vested During Period Shares Restricted Common Stock Award
Issuance of common stock upon vesting of RSUs (in shares)
Represents the number of votes per share each holder of shares is entitled to.
Equity Instrument Voting Rights Per Share
Common stock, voting right per share
Increase (Decrease) in Accounts Payable
Accounts payable
Increase (Decrease) in Accounts Payable, Total
Entity Address, Address Line Two
Entity Address, Address Line Two
Liabilities and Equity [Abstract]
Liabilities and stockholders’ equity
Document Period End Date
Document Period End Date
Net Cash Provided by (Used in) Financing Activities
Net cash provided by financing activities
Add: accreted final payment fee
Debt Instrument Accreted Final Payment Fee
Debt instrument accreted final payment fee.
Effective tax rate
Effective Income Tax Rate Reconciliation, Percent
Effective tax rate
Effective Income Tax Rate Reconciliation, Percent, Total
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Antidilutive securities
The minimum percentage of cash to be maintained under debt instruments.
Long Term Debt Additional Drawn Covenant Minimum Cash To Be Maintained As Security Percent
Minimum percentage of cash to be maintained as a security
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition
Stock-based compensation
APIC, Share-based Payment Arrangement, Increase for Cost Recognition, Total
Income tax benefit (expense)
Provision for income taxes
Income tax expense
Income Tax Expense (Benefit)
Income Tax Expense (Benefit), Total
Income tax benefit (expense)
Cash Equivalents, at Carrying Value [Abstract]
Cash Equivalents
Tranche One
Tranche One [Member]
Tranche one.
SVB Securities Limited Liability Company.
SVB Securities Limited Liability Company [Member]
SVB Securities
Trading Symbol
Trading Symbol
Business Combination
Business Combinations [Abstract]
Variable Rate [Axis]
Variable Rate
Equity, Attributable to Parent
Ending balance
Beginning balance
Total stockholders’ equity
Term Loan Advances
Term Loan Advances [Member]
Term loan advances.
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward]
Number of shares
Operating lease, expiration month and year.
Operating Lease Expiration Month And Year
Operating lease, expiration month and year
Long-Lived Tangible Asset [Axis]
Lessee operating lease liability payments due after year four.
Lessee Operating Lease Liability Payments Due After Year Four
Thereafter
Class of Warrant or Right, Outstanding
Warrants outstanding beginning balance
Warrants outstanding ending balance
Stock-Based Compensation
Share-Based Payment Arrangement [Policy Text Block]
Cash at settlement
Cash paid for business combination
Payments to Acquire Businesses, Gross
Restricted Stock Units (RSUs) [Member]
Restricted Stock Units
Related Party Transactions [Abstract]
Royalty Agreements [Abstract]
Royalty agreements.
Goodwill, ending balance
Goodwill, beginning balance
Balance at December 31,2021
Goodwill
Goodwill, Total
Goodwill Remain Unchanged
Initial Cash Payment Per Collaboration Agreement.
Initial Cash Payment Per Collaboration Agreement
Upfront cash payment
Represents the maximum reduction percentage of the royalty due as a result of required payments to third parties.
License Agreement Royalty Due Maximum Reduction Percentage As Result Of Required Payments To Third Parties
License agreement royalty, maximum reduction percent as a result of required third party payments
Contract With Customer Liability [Line Items]
Contract With Customer Liability [Line Items]
Contract with customer liability.
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
Schedule of Stock-Based Compensation Expense Recognized
Measurement Input Discount Rate
Measurement Input, Discount Rate [Member]
Schedule of Accounts Receivable, Net
Schedule of Accounts, Notes, Loans and Financing Receivable [Table Text Block]
Measurement Input Type [Axis]
Rule 10b5-1 Trading Plan Two
Rule 10b5-1 Trading Plan Two [Member]
Rule 10b5-1 Trading Plan Two
Unobservable input weighted average rate
Unobservable Input Weighted Average Rate
Unobservable input weighted average rate.
Geographical [Axis]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Aggregate Intrinsic Value
Aggregate intrinsic value, Exercisable
Finance Lease, Liability, to be Paid, Year Three
2027
Share-Based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount
Unrecognized compensation cost related to non-vested stock options expected to be recognized
Antecip.
Affiliated Entity [Member]
Antecip
Use of Estimates, Policy [Policy Text Block]
Use of Estimates
Concentration risk, percentage
Concentration Risk, Percentage
Cash and Cash Equivalents, Policy [Policy Text Block]
Cash and Cash Equivalents
Non-current inventory and other assets
Weighted average price at which warrants were exercised.
Warrants Exercised In Period Weighted Average Exercise Price
Exercised
Period during which warrants are active, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.
Class Of Warrant Or Right Term
Term of warrants (in years)
Scenario [Axis]
Scenario
Tranche One Sub Tranche Four
Tranche One Sub Tranche Four [Member]
Tranche one sub tranche four.
Security Exchange Name
Security Exchange Name
Counterparty Name [Domain]
Counterparty Name
Fair Value by Liability Class [Domain]
Business Acquisition, Acquiree [Domain]
Tranche One Sub Tranche Two
Tranche One Sub Tranche Two [Member]
Tranche one sub tranche two.
Long-Lived Tangible Asset [Domain]
Share-based compensation arrangement by share-based payment award options forfeitures or canceled in period, weighted average exercise price.
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures Or Canceled in Period, Weighted Average Exercise Price
Weighted average exercise price, Forfeited/Canceled
Fair Value of Financial Instruments
Fair Value Disclosures [Text Block]
Lessee, Operating Lease, Liability, to be Paid, Year Three
2027
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value
Weighted average grant date fair value
Research and Development Arrangement, Contract to Perform for Others, Type [Domain]
Research and Development Arrangement, Contract to Perform for Others, Type
Adjustments to Additional paid-in capital Shares tendered for withholding taxes.
Adjustments To Additional Paid In Capital Shares Tendered For Withholding Taxes
Shares tendered for withholding taxes
Maximum
Maximum
Liabilities and Equity
Total liabilities and stockholders’ equity
Operating Lease, Right-of-Use Asset
Right-of-use asset - operating lease
Operating lease, right-of-use asset
Supplemental Cash Flow Information [Abstract]
Supplemental disclosures of cash flow information:
Prime Rate [Member]
Prime Rate
Net loss per common share, diluted
Earnings Per Share, Diluted
Earnings Per Share, Diluted, Total
Percentage of facility fee to be paid
Percentage Of Facility Fee To Be Paid
Percentage of facility fee to be paid.
Liabilities
Total liabilities
Research and Development [Abstract]
Schedule of interest expense and amortization of final payment fee, amortization of debt discount related to issuance costs and warrants.
Schedule of Interest Expense and Amortization of Final Payment Fee, Amortization of Debt Discount Related to Issuance Costs and Warrants [Table Text Block]
Schedule of Interest Expense and Amortization of Final Payment Fee, Amortization of Debt Discount Related to Issuance Costs and Warrants
Fair Value Hierarchy and NAV [Domain]
Accrued selling, general and administrative
Accrued Selling, General and Administrative Current
Accrued selling, general and administrative current.
Assets, Current
Total current assets
Net Cash Provided by (Used in) Investing Activities
Net cash used in investing activities
Forecast [Member]
Scenario Forecast
Stock Issued During Period, Shares, New Issues
Shares issued
Revenue Discount Rate Increases or Decreases by Approximately 1%
Revenue Discount Rate Increases or Decreases by One Percentage [Member]
Revenue discount rate increases or decreases by one percentage.
December two thousand nineteen and march two thousand twenty two sales agreement.
December Two Thousand Nineteen and March Two Thousand Twenty Two Sales Agreement [Member]
December 2019 and March 2022 Sales Agreement
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period
Vesting period
Lessee, Operating Lease, Existence of Option to Extend [true false]
Lessee, operating lease, existence of option to extend [true false]
Entity Filer Category
Entity Filer Category
Equipment, net
Property, Plant and Equipment [Abstract]
Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block]
Nature of Business and Basis of Presentation
Unrecognized tax benefits
Unrecognized Tax Benefits that Would Impact Effective Tax Rate
Fair Value, Assets and Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Abstract]
Current Fiscal Year End Date
Current Fiscal Year End Date
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Equipment, net
Property, Plant and Equipment, Policy [Policy Text Block]
Lessee, Operating Lease, Liability, Undiscounted Excess Amount
Less imputed interest
Term Loan 2020
Represents about term loan two thousand twenty.
Term Loan2020 [Member]
Share-Based Payment Arrangement, Noncash Expense
Stock-based compensation expense
Share-based Payment Arrangement, Noncash Expense, Total
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value
Aggregate intrinsic value, Outstanding
Related and Nonrelated Parties [Axis]
Related Party
Interest Expense, Debt, Excluding Amortization
Interest expense
Accrued contingent consideration, current
Contingent consideration, current
Business Combination, Contingent Consideration, Liability, Current
Entity Registrant Name
Entity Registrant Name
Contingent consideration liability
Contingent consideration
Contingent Consideration Liability, Total
Fair value of contingent consideration
Finance Lease, Weighted Average Remaining Lease Term
Weighted average remaining lease term
Cost of product sales
Cost of product sales
Cost of Revenue
Cost of Revenue, Total
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Earnings Per Share [Text Block]
Net Loss per Common Share
Entity Emerging Growth Company
Entity Emerging Growth Company
Represents the number of license agreements the Company has entered into.
Number Of License Agreements
Number of exclusive license agreements
Money Market Funds
Money Market Funds [Member]
Weighted average common shares outstanding, basic
Weighted Average Number of Shares Outstanding, Basic
Weighted Average Number of Shares Outstanding, Basic, Total
Loss Contingencies [Line Items]
Loss Contingencies [Line Items]
Finance Lease, Liability, Noncurrent
Finance lease liability, long-term
Lessee, Operating Lease, Liability, to be Paid, Fiscal Year Maturity [Abstract]
Operating Lease
Common Stock, Shares Authorized
Common stock, shares authorized
Interest Payable, Current
Accrued interest
Property, Plant and Equipment, Useful Life
Estimated useful life
Schedule of Long-Term Debt Instruments [Table Text Block]
Schedule of Outstanding Debt and Unamortized Debt Discount Balances
Royalty Revenue
Royalty [Member]
Proceeds from issuance of common stock upon financing
Proceeds from Issuance of Common Stock
Proceeds from Issuance of Common Stock
Concentration Risk Type [Axis]
Finance Lease, Interest Expense
Interest on lease liabilities
Level 1
Fair Value, Inputs, Level 1 [Member]
Discount Rate Increases or Decreases by Approximately 1%
Discount Rate Increases or Decreases by One Percentage [Member]
Discount rate increases or decreases by one percentage.
License agreement royalty as a percent of net sale
Represents the percentage of net sales of products containing the licensed products, due to licensor as a royalty.
License Agreement Royalty Due Percentage Of Net Sales
License agreement royalty as a percent of net sales
Debt Disclosure [Abstract]
Long-Term Debt [Text Block]
Loan and Security Agreement
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price
Weighted average exercise price, Vested and expected to vest
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Weighted average exercise price, Granted
Amortization Expense
Intangible asset amortization
Amortization of intangible asset
Amortization expense
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Weighted average contractual term, Outstanding
Earnings Per Share, Policy [Policy Text Block]
Basic and Diluted Net Loss per Common Share
Debt, Policy [Policy Text Block]
Debt Issuance Costs
General and Administrative Expense [Member]
Selling General and Administrative
Revenue Recognition
Revenue [Policy Text Block]
Number of shares of stock issued during the period pursuant to a financing arrangement.
Stock Issued During Period Shares Financing
Issuance of common stock upon financing (in shares)
Issuance of common stock
Payment Of Contingent Consideration
Payment of contingent consideration
Tranche One Sub Tranche One
Tranche One Sub Tranche One [Member]
Tranche One Sub Tranche One [Member]
Warrant liability.
Warrant Liability [Member]
Warrant liability
Eligible to receive sales-based and other milestones
Eligible to receive sales-based and other milestones
Eligible to receive sales-based and other milestones
Accounting Policies [Abstract]
Represents information pertaining to AXS-04.
Axs04 [Member]
AXS-04
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
Summary of Stock Option Activity
Finance Lease, Liability, to be Paid, Remainder of Fiscal Year
2024
Represents the information pertaining to AXS-05 and AXS-07.
Axs05 And Axs07 [Member]
AXS-05 and AXS-07
Tranche One Sub Tranche Five
Tranche One Sub Tranche Five [Member]
Tranche one sub tranche five.
Finance lease costs.
Finance Lease Costs [Abstract]
Finance lease expense
Income Tax Disclosure [Abstract]
Equity, Attributable to Parent [Abstract]
Stockholders’ equity:
Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract]
Supplemental non-cash investing activities:
Statement [Table]
Statement [Table]
Segment Reporting, Policy [Policy Text Block]
Segment Information
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term
Weighted average contractual term, Vested and expected to vest
Inventory Write-down
Inventory write down
Threshold period of specified consecutive trading days within which the volume weighted average price of company's common stock.
Class Of Warrants Or Rights Weighted Average Price Trading Days
Trading days
Accrued Liabilities and Other Liabilities [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract]
Weighted average exercise price
Sunosi.
Sunosi [Member]
Sunosi
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest [Abstract]
Aggregate intrinsic value
Preferred Stock, Shares Authorized
Preferred stock, shares authorized
Securities Act File Number
Entity File Number
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect
Net (decrease) increase in cash
Revenue from Contract with Customer [Abstract]
Earnings Per Share [Abstract]
Leased office space.
Leased Office Space [Member]
22 Cortlandt Street Lease
Inventory Disclosure [Abstract]
Operating Lease, Liability, Statement of Financial Position [Extensible Enumeration]
Statement of Financial Position [Abstract]
Loss from operations
Operating Income (Loss)
Loss from operations
Long-Term Debt, Maturity, Year One
2024
Entity Shell Company
Entity Shell Company
Line of Credit Facility [Table]
Line Of Credit Facility [Table]
Schedule of fair value measurements of contingent consideration recurring include significant unobservable inputs
Fair Value Measurement Inputs and Valuation Techniques [Table Text Block]
Entity Tax Identification Number
Entity Tax Identification Number
Assets [Abstract]
Assets
Entity Current Reporting Status
Entity Current Reporting Status
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term
Weighted average contractual term, Exercisable
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Research And Development Arrangement Contract To Perform For Others [Line Items]
Finance Lease, Liability, to be Paid, Year Four
2028
Long-Term Debt, Type [Axis]
Long-Term Debt, Type
Inventory
Inventory Disclosure [Text Block]
Geographical [Domain]
Document Fiscal Year Focus
Document Fiscal Year Focus
Preferred Stock, Value, Issued
Preferred Stock, Value, Issued, Ending Balance
Preferred Stock, Value, Issued, Total
Preferred Stock, Value, Issued, Beginning Balance
Preferred stock, $0.0001 par value per share (10,000,000 shares authorized, none issued and outstanding)
The minimum percentage of cash to be maintained as security following the market capitalization conditions under the debt instruments.
Long Term Debt Additional Drawn Covenant Minimum Cash To Be Maintained As Security With Market Capitalization Covenant Percent
Minimum percentage of cash to be maintained as a security following market capitalization condition
Lessee, Finance Lease, Term of Contract
Finance lease, lease terms
Finite-Lived Intangible Assets, Accumulated Amortization
Accumulated amortization
Cost of Revenue
Cost of Goods and Service [Policy Text Block]
Business Acquisition [Axis]
City Area Code
City Area Code
Reclassifications
Reclassification, Comparability Adjustment [Policy Text Block]
Liabilities, Current
Total current liabilities
Cost of Product Sales
Cost of Revenue [Abstract]
Line of Credit Facility, Lender [Domain]
Line of Credit Facility, Lender
Inventories, net
Inventory, Net
Inventories, net
Finished goods
Inventory, Finished Goods, Gross
Number of approved products.
Number of approved products
Debt Instrument, Unamortized Discount, Noncurrent
Less: unamortized debt discount, long-term
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Local Phone Number
Local Phone Number
Preferred Stock, Shares Outstanding
Preferred stock, shares outstanding
Preferred Stock, Shares Outstanding, Beginning Balance
Preferred Stock, Shares Outstanding, Ending Balance
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Sublease agreement term.
Sublease Agreement Term
Sublease agreement term
Milestone dates
Milestone Dates [Member]
Milestone dates [Member].
Fair Value Measurement Inputs and Valuation Techniques [Abstract]
Represents the information if the outstanding principle and advances under loan agreement exceeds fifty five million.
Outstanding Advances Under Loan Agreement Equals Or Exceeds Fifty Five Million [Member]
Outstanding principle and advances under the loans agreement exceeds 55 million
Tranche Two Sub Tranches To One Tranche
Tranche Two Sub Tranches To One Tranche [Member]
Tranche two sub tranches to one tranche.
Income Tax, Policy [Policy Text Block]
Income Taxes
Commitments and Contingencies Disclosure [Abstract]
Fair Value, by Balance Sheet Grouping [Table]
Increase in minimum cash requirement amount
Long Term Debt Additional Drawn Covenant Minimum Cash
Long Term debt additional drawn covenant minimum cash.
Operating Lease, Liability, Current
Operating lease liability, current portion
Right-of-Use Asset Obtained in Exchange for Finance Lease Liability
Finance lease right-of-use asset obtained in exchange for finance lease liability
Finance lease right-of-use asset recognized during period
Debt Instrument, Interest Rate, Stated Percentage
Base interest rate
Retained Earnings [Member]
Accumulated Deficit
Payments to Acquire Property, Plant, and Equipment
Purchases of equipment
Payments to Acquire Property, Plant, and Equipment, Total
Document Transition Report
Document Transition Report
Other Noncash Investing and Financing Items [Abstract]
Supplemental disclosures of non-cash financing activity:
Other two products
Other Two Products [Member]
Other Two Products
Share-Based Compensation Arrangement by Share-Based Payment Award, Purchase Price of Common Stock, Percent
Purchase price of common stock percent
Lessee, Operating Lease, Liability, to be Paid, Year Two
2026
Valuation Approach and Technique [Domain]
Antidilutive Security, Excluded EPS Calculation [Table]
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Number of reporting units
Number of Reporting Units
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Weighted average exercise price, Exercised
Concentration of Risk
Concentration Risk, Credit Risk, Policy [Policy Text Block]
Finite-Lived Intangible Asset, Expected Amortization, Remainder of Fiscal Year
2024
Minimum
Minimum
Common Stock [Member]
Common Stock
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]
Long-Term Debt, Maturity, Year Two
2025
Accounts Payable and Accrued Liabilities Disclosure [Text Block]
Accrued Expenses and Other Current Liabilities
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value
Aggregate intrinsic value, Vested and expected to vest
Fair value of contingent consideration in a business combination.
Fair Value Of Contingent Consideration In A Business Combination
Fair value of contingent consideration in a business combination
Investment, Name [Axis]
Investment, Name
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value
Weighted average grant date fair value, Outstanding, ending balance
Weighted average grant date fair value, Outstanding, beginning balance
Change in operating lease liability.
Change In Operating Lease Liability
Change in operating lease liability
Additional Paid-in Capital [Member]
Additional Paid-in Capital
Foreign Currency Transactions and Translations Policy [Policy Text Block]
Foreign Currency Translation
Statement of Income Location, Balance [Domain]
Income Statement Location
Lessee, Operating Lease, Liability, to be Paid, Year One
2025
Fair Value Measurement With Unobservable Inputs Reconciliations Recurring Basis Liability Initial Estimate
Fair value measurement with unobservable inputs reconciliations recurring basis liability initial estimate.
Initial estimate (Level 3)
Disclosure of accounting policy for significant risks and uncertainties.
Significant Risks And Uncertainties Policy Policy [Text Block]
Significant Risks And Uncertainties
Total Pursuant To Non-Qualified Stock Options
Total Pursuant To Non- Qualified Stock Options [Member]
Total Pursuant To Non- Qualified Stock Options
Schedule of Inventory
Schedule of Inventory, Current [Table Text Block]
Customer One
Customer One [Member]
Customer One.
Entity Common Stock, Shares Outstanding
Entity Common Stock, Shares Outstanding
Disaggregation of Revenue [Line Items]
Operating Sub Lease commencement Month and Year.
Operating Sub Lease commencement Month and Year
Operating sub Lease commencement month and year
Accounts and Financing Receivables [Table]
Issuance of warrants upon debt financing
Warrants issued during period debt financing.
Warrants Issued During Period Debt Financing
Finite-Lived Intangible Asset, Expected Amortization, Year One
2025
Scenario [Domain]
Scenario
Number of warrants (or share units) issued during the current period.
Warrants Issued In Period
Number of warrants issued
Issued
Finance Lease, Liability, Current
Finance lease liability, current
Accrued sales discounts, rebates and allowances
Accrued Sales Commission, Current
Common stock, $0.0001 par value per share (150,000,000 shares authorized, 47,801,578 and 47,351,363 shares issued and outstanding at June 30, 2024 and December 31, 2023, respectively)
Common Stock, Value, Issued
Value of common stock
Common Stock, Value, Issued, Total
Common Stock, Value, Issued, Beginning Balance
Common Stock, Value, Issued, Ending Balance
Tranche Three Sub Tranches to One Tranche
Tranche Three Sub Tranches To One Tranche [Member]
Tranche three sub tranches to one tranche.
Finance Lease, Right-of-Use Asset, Amortization
Right-of-use asset amortization for finance lease
Amortization of right-of-use assets
Schedule of Finite-Lived Intangible Assets, Future Amortization Expense [Table Text Block]
Schedule of Finite Lived Intangible Assets Future Amortization Expenses
Pharmanovia
Pharmanovia [Member]
Pharmanovia.
Cash and cash equivalents
Cash and Cash Equivalents, Fair Value Disclosure
Represents the consecutive number of trading days to determine the weighted average price per share of ordinary shares.
Consecutive Trading Days
Prior trading days
Long-Term Debt, Maturity, Year Three
2026
Contingent Consideration Type [Domain]
Operating Lease, Liability
Present value of operating lease liabilities
Operating Lease, Liability, Total
Operating lease liability
Period of time, after the first commercial sale of the applicable product, the license agreement is valid, in PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.
License Agreement Term
License agreement term, from first commercial sale
Measurement Frequency [Axis]
Schedule of Accrued Liabilities [Table Text Block]
Schedule of Accrued Expenses and Other Current Liabilities
Schedule of Interest and Amortization Expense for Final Payment Fee and Debt Discount
Schedule of Interest and Amortization Expense for Final Payment Fee and Debt Discount [Table Text Block]
Schedule of interest and amortization expense for final payment fee and debt discount.
Customer Three
Customer Three [Member]
Customer Three.
Tranche One Sub Tranche Three
Tranche One Sub Tranche Three [Member]
Tranche one sub tranche three.
Weighted average common shares outstanding, diluted
Weighted Average Number of Shares Outstanding, Diluted
Weighted Average Number of Shares Outstanding, Diluted, Total
Significant Accounting Policies [Text Block]
Summary of Significant Accounting Policies
Number of not yet approved product candidates.
Number of Not Yet Approved Product Candidates
Number of not yet approved product candidates
Accounts Receivables, net
Accounts receivables, net
Accounts Receivable, after Allowance for Credit Loss, Current
Accounts receivable, net
Research and Development Arrangement, Contract to Perform for Others, Type [Axis]
Research and Development Arrangement, Contract to Perform for Others, Type
Lessee, Operating Lease, Renewal Term
Operating lease, renewal term
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number
Number of shares, Vested and expected to vest
Lessee, Operating Lease, Liability, to be Paid
Total lease payments
Inventories, net
Increase (Decrease) in Inventories
Increase (Decrease) in Inventories, Total
Proceeds from issuance of common stock upon exercise of options and under employee stock purchase plan
Proceeds From Issuance Of Common Stock Upon Exercise Of Options And Under Employee Stock Purchase Plan
Proceeds from issuance of common stock upon exercise of options and under employee stock purchase plan.
Hercules Capital Inc.
Hercules Capital Inc [Member]
Hercules Capital Inc
Concentration Risk Benchmark [Domain]
Finance Lease, Liability, Total
Finance Lease, Liability
Finance lease liabilty
Entity Small Business
Entity Small Business
Debt Instrument, Basis Spread on Variable Rate
Interest rate basis
Segment Reporting, Disclosure of Entity's Reportable Segments [Abstract]
Segment and Geographic Information
March Two Thousand Twenty Two Sales Agreement [Member]
March Two Thousand Twenty Two Sales Agreement [Member]
March 2022 Sales Agreement
Represents the prepayment penalty percentage on principal amount of debt.
Debt Instrument Prepayment Penalty Percentage
Percentage of prepayment penalty
The minimum amount of cash should be maintained as first priority security interest under the terms of debt instrument.
Long Term Debt Additional Drawn Covenant Minimum Cash As Security Interest
Minimum cash to be maintain as a first priority security interest
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Expirations in Period, Weighted Average Exercise Price
Weighted average exercise price, Expired
Non-cash lease expense.
Non Cash Lease Expense
Non-cash lease expense
Net Cash Provided by (Used in) Financing Activities [Abstract]
Cash flows from financing activities
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Weighted average exercise price, Outstanding, ending balance
Weighted average exercise price, Outstanding, beginning balance
Amortization of debt discount related issuance costs and warrants
Amortization of Debt Discount (Premium)
Amortization of debt discount
Asset Class [Axis]
Tranche Two Sub Tranche Three
Tranche two sub tranche three.
Tranche Two Sub Tranche Three [Member]
Net Book Value at September 30, 2023
Net Book Value at March 31, 2023
Balance at December 31, 2022
Intangible asset, net
Intangible Assets, Net (Excluding Goodwill)
Net carrying amount
Expected cash dividend
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Payments
Right-of-Use Asset Obtained in Exchange for Operating Lease Liability
Operating lease right-of-use asset obtained in exchange for operating lease liability
Measurement Frequency [Domain]
Work in process
Inventory, Work in Process, Gross
Level 3
Fair Value, Inputs, Level 3 [Member]
Operating Lease, Weighted Average Remaining Lease Term
Operating lease, remaining lease term
Accounts Payable, Current
Accounts payable
Accounts Payable, Current, Total
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value [Abstract]
Weighted average grant date fair value
June two thousand twenty three public offering.
June Two Thousand Twenty Three Public Offering [Member]
June 2023 Public Offering
Total operating expenses
Costs and Expenses
Total
Liabilities, Fair Value Disclosure
Cardinal Health, Inc Cencora, Inc And Mckesson Corporation
Cardinal Health, Inc Cencora, Inc And Mckesson Corporation [Member]
Cardinal Health, Inc Cencora, Inc And Mckesson Corporation.
Risks and Uncertainties [Abstract]
Concentration of Credit Risk
Accounts receivable, Allowance for credit loss
Accounts Receivable, Allowance for Credit Loss
Accounts Receivable, Allowance for Credit Loss, Ending Balance
Accounts Receivable, Allowance for Credit Loss, Beginning Balance