Entity Address, City or Town
Entity Address, City or Town
Debt instrument prepayment occurring prior to first anniversary of first amendment closing date.
Debt Instrument Prepayment Occurring Prior To First Anniversary Of First Amendment Closing Date [Member]
Prepayment Occurs Prior to First Anniversary of First Amendment Closing Date
Fair Value Disclosures [Abstract]
Earnings Per Share [Abstract]
Level 1
Fair Value, Inputs, Level 1 [Member]
Schedule of Accrued Liabilities [Table Text Block]
Schedule of Accrued Expenses
Fair value of issued nonredeemable common stock (or common stock redeemable solely at the option of the issuer). This item includes treasury stock repurchased by the entity. Note: elements for number of nonredeemable common shares, par value and other disclosure concepts are in another section within stockholders' equity.
Common Stock Fair Value
Fair value of common stock
Stock Issued During Period, Value, New Issues
Proceeds from issuance of common stock, gross
Research and Development Expense, Policy [Policy Text Block]
Research and Development Costs
Net Cash Provided by (Used in) Financing Activities [Abstract]
Cash flows from financing activities
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Outstanding, Weighted Average Remaining Contractual Terms
Weighted average contractual term
License Agreement Terms [Member]
License Agreement
Long-term Line of Credit, Total
Long-Term Line of Credit
Line of credit
Amendment Flag
Amendment Flag
Less: non-operating assets, net of liabilities
Less: non-operating assets, net of liabilities
Business Combination, Non-Operating Assets, Net Of Liabilities
Business combination, non-operating assets, net of liabilities.
Inventory [Line Items]
Long-Term Debt, Maturity, Year Four
2026
Research and Development [Abstract]
Accumulated Amortization
Finite-Lived Intangible Assets, Accumulated Amortization
2022 warrants
Term Loan Two Thousand and Twenty Two Warrants [Member]
Term loan two thousand and twenty two warrants.
Goodwill, ending balance
Goodwill, beginning balance
Balance at December 31,2021
Goodwill
Goodwill
Goodwill, Total
Operating Lease, Right-of-Use Asset
Right-of-use asset - operating lease
Schedule of Net Book Value of our Intangible Asset
Schedule of Finite-Lived Intangible Assets [Table Text Block]
Document Quarterly Report
Document Quarterly Report
Lessee, Operating Lease, Liability, Undiscounted Excess Amount
Less imputed interest
Earnings Per Share, Policy [Policy Text Block]
Basic and Diluted Net Loss per Common Share
Percentage of discount rate intangible asset measurement input
Percentage of Discount Rate Intangible Asset Measurement Input
Percentage of discount rate intangible asset measurement input.
Inventory, Current [Table]
Statement [Table]
Statement [Table]
Operating Lease, Liability, Noncurrent
Operating lease liability, long-term
Number of days to achieve second milestone following such date.
Threshold Days To Achieve Second Milestone
Period to achieve second milestone
The authorized amount under a common stock sales agreement.
Common Stock Sales Agreement Authorized Amount
Common stock sales agreement, authorized amount
Change in Accounting Principle, Accounting Standards Update, Immaterial Effect [true false]
Change in accounting principle, accounting standards update, immaterial effect
Number of Operating Segments
Number of operating segments
Preferred Stock, Shares Outstanding
Preferred stock, shares outstanding
Preferred Stock, Shares Outstanding, Beginning Balance
Preferred Stock, Shares Outstanding, Ending Balance
Business Acquisition [Axis]
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value
Weighted average grant date fair value, Outstanding, ending balance
Weighted average grant date fair value, Outstanding, beginning balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value
Weighted average grant date fair value, Vested
Debt instruments maturity, month and year.
Debt Instruments Maturity Month And Year
Debt instrument maturity, month and year
Inventory
Inventory fair value step-up on inventory acquired
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Inventory
2020 warrants
Represents about term loan tranche one.
Term Loan2020 Tranche One [Member]
Term loan 2020 tranche one
Line of Credit Facility [Line Items]
Line Of Credit Facility [Line Items]
Business Combination
Business Combination Disclosure [Text Block]
Long term debt increase decrease threshold amount
Long Term Debt Increase Decrease Threshold Amount
Long term debt increase decrease threshold amount.
Accounting Standards Update 2019-12 [Member]
2019-12
Product and Service [Axis]
Product and Service
Debt, Policy [Policy Text Block]
Debt Issuance Costs
Contingent consideration liability
Contingent consideration
Contingent Consideration Liability, Total
Fair value of contingent consideration
Remaining Weighted-Average Useful Life
Intangible assets, Estimated period of benefit
Finite-Lived Intangible Asset, Useful Life
Employee-related Liabilities, Current
Accrued compensation
Employee-related Liabilities, Current, Total
Represents the number of late-stage candidates included in the Company's product candidate portfolio.
Number Of Late Stage Product Candidates
Number of late-stage candidates in Company's product candidate portfolio
Share-Based Payment Arrangement, Option [Member]
Stock Options
Prepayment Occurs on or After Second Anniversary and Prior to Third Anniversary of First Amendment Closing Date
Debt instrument prepayment occurs on or after second anniversary and prior to third anniversary of first amendment closing date.
Debt Instrument Prepayment Occurs On Or After Second Anniversary And Prior To Third Anniversary Of First Amendment Closing Date [Member]
Operating Lease, Weighted Average Remaining Lease Term
Operating lease, remaining lease term
Liabilities and Equity
Total liabilities and stockholders’ equity
Inventories, net
Inventory, Policy [Policy Text Block]
Sample inventory
Sample Inventory
Sample inventory.
Plan Name [Domain]
Plan Name
Line of Credit Facility, Lender [Domain]
Type of Cost Good or Service [Extensible List]
Cost, Product and Service [Extensible Enumeration]
Raw materials
Inventory, Raw Materials, Gross
Represents about term loan tranche two.
Term Loan2020 Tranche Two [Member]
Term loan 2020 tranche two
Change in Accounting Principle, Accounting Standards Update, Adopted [true false]
Change in accounting principle, accounting standards update, adopted
Discount rate
Measurement Input, Discount Rate [Member]
Entity Incorporation, State or Country Code
Entity Incorporation, State or Country Code
Income Statement [Abstract]
Effective cash pay interest rate for the funds borrowed under the debt agreement considering interest compounding and original issue discount or premium.
Debt Instrument Threshold Cash Pay Interest Rate
Cash pay interest rate
Tranche two sub tranche one.
Tranche Two Sub Tranche One [Member]
Tranche Two Sub-Tranche One
Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block]
Nature of Business and Basis of Presentation
Goodwill [Abstract]
Goodwill [Abstract].
The final payment fee at extinguishment of debt.
Extinguishment Of Debt Fee Amount
Final payment fee
Sale of Stock [Domain]
Sale of Stock
Contingent consideration
Contingent Consideration [Member]
Contingent consideration [Member].
Liabilities, Current
Total current liabilities
Business Combination
Business Combinations Policy [Policy Text Block]
The amount of future payments payable under the collaboration arrangement.
Collaboration Arrangement Future Potential Payments
Future milestone payments
The minimum amount of market capital to be maintained under debt instruments.
Long Term Debt Additional Drawn Covenant Minimum Market Capitalization Amount
Minimum amount of market capital to be maintained
Lessee, Operating Lease, Liability, to be Paid, Year Three
2025
Business Acquisition, Acquiree [Domain]
Fair Value, Recurring [Member]
Accounts receivable, Allowance for credit loss
Accounts Receivable, Allowance for Credit Loss
Accounts Receivable, Allowance for Credit Loss, Ending Balance
Accounts Receivable, Allowance for Credit Loss, Beginning Balance
Accounts Payable and Accrued Liabilities Disclosure [Text Block]
Accrued Expenses and Other Current Liabilities
Income Tax, Policy [Policy Text Block]
Income Taxes
Adjustments, Noncash Items, to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract]
Adjustments to reconcile net loss to net cash used in operating activities:
Preferred Stock, Shares Authorized
Preferred stock, shares authorized
Minimum different from remaining percentage of cash flow
Long Term Debt Different From Remaining Drawn Covenant Minimum Cash Flow Percentage
Long term debt different from remaining drawn covenant minimum cash flow percentage.
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table]
Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table]
Operating Lease, Weighted Average Discount Rate, Percent
Operating lease, discount rate
Investment, Name [Domain]
Investment, Name
Type of Revenue [Extensible List]
Revenue, Product and Service [Extensible Enumeration]
Variable Rate [Axis]
Variable Rate
Entity Small Business
Entity Small Business
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Total
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents
Cash at beginning of period
Cash at end of period
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Collaborative Arrangement and Arrangement Other than Collaborative
Fair Value Measurement Inputs and Valuation Techniques [Table]
The fair value of outstanding warrants.
Fair Value Of Warrants
Fair value
Revenue milestones.
Revenue Milestones
Revenue milestones
Intangible Asset
Intangible Assets Disclosure [Text Block]
The period of unpaid invoices after threshold period respective amount should be keep as a security under the debt instruments.
Long Term Debt Additional Drawn Covenant Additional Security Unpaid Invoices Period
Period of unpaid invoices amount maintain as security
Unobservable input weighted average term
Unobservable Input Weighted Average Term
Unobservable input weighted average term.
Represents the prepayment of debt occurring prior to first anniversary of closing date.
Debt Instrument Prepayment Occurring Prior To First Anniversary Of Closing Date [Member]
Prepayment Occurs Prior to First Anniversary of Closing Date
Subject to FDA approval of AXS zero five and AXS zero seven.
Subject To FDA Approval Of AXS Zero Five And AXS Zero Seven [Member]
Subject to FDA Approval of AXS-05 and AXS-07
Represents information pertaining to AXS-02.
Axs02 [Member]
AXS-02
Assets, Current
Total current assets
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest [Abstract]
Aggregate intrinsic value
Lessee, Operating Lease, Liability, to be Paid, Remainder of Fiscal Year
2022
Intangible Assets [Abstract]
Intangible Assets Abstract.
Weighted average common shares outstanding, basic
Weighted Average Number of Shares Outstanding, Basic
Weighted Average Number of Shares Outstanding, Basic, Total
Change in fair value of contingent consideration
Change in fair value of contingent consideration
Change in fair value of contingent consideration
Change In Fair Value Of Contingent Considerations
Change in fair value of contingent considerations.
City Area Code
City Area Code
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value
Aggregate intrinsic value, Outstanding
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period
Number of shares, Forfeited
Tranche three sub tranche one.
Tranche Three Sub Tranche One [Member]
Tranche Three Sub Tranche One
Weighted average price at which warrants were issued.
Warrants Issued In Period Weighted Average Exercise Price
Issued (in dollars per share)
SVB Leerink limited liability company.
Leerink Partners Limited Liability Company [Member]
SVB Leerink
Liabilities
Total liabilities
Document Period End Date
Document Period End Date
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value
Weighted average grant date fair value
Risks and Uncertainties [Abstract]
Concentration of Credit Risk
2022
Finite-Lived Intangible Asset, Expected Amortization, Year One
Statistical Measurement [Axis]
Statistical Measurement
Effective Income Tax Rate Reconciliation, Percent [Abstract]
Income Taxes
Thereafter
Finite-Lived Intangible Asset, Expected Amortization, after Year Five
Related Party [Axis]
Related Party
Assets
Total assets
The commission percentage paid under a common stock sales agreement.
Common Stock Sales Agreement Commission Percentage
Common stock sales agreement, commission percentage
Long-Term Debt, Excluding Current Maturities
Loan payable, long-term
Loan payable, long-term
The entire disclosure for license agreements.
License Agreements Disclosure [Text Block]
License Agreements
Net loss per common share, diluted
Earnings Per Share, Diluted
Earnings Per Share, Diluted, Total
Accounts Receivable, net
Accounts Receivable [Policy Text Block]
Share based compensation arrangement by share based payment award options expired in period.
Share Based Compensation Arrangement By Share Based Payment Award Options Expired In Period
Number of shares, Expired
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Schedule of Potentially Dilutive Securities
Debt Instrument, Unamortized Discount, Noncurrent
Less: unamortized debt discount, long-term
Fair value of contingent consideration
Ending Balance
Beginning Balance
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability Value
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Entity Address, Postal Zip Code
Entity Address, Postal Zip Code
Document Fiscal Period Focus
Document Fiscal Period Focus
Represents the number of financial institutions holding the Company's cash.
Number Of Financial Institutions Holding Deposits
Number of financial institutions that hold the Company's cash
Value of stock issued pursuant to a financing arrangement during the period.
Stock Issued During Period Value Financing
Issuance of common stock upon financing
Accrued expenses and other current liabilities
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Current Liabilities, Accrued Expenses and Other Current Liabilities
Business combination, recognized identifiable assets acquired and liabilities assumed, current liabilities, accrued expenses and other current liabilities.
Accounts receivable, net
Increase (Decrease) in Accounts Receivable
Preferred stock, $0.0001 par value per share (10,000,000 shares authorized, none issued and outstanding at June 30, 2022 and December 31, 2021, respectively)
Preferred Stock, Value, Issued
Preferred Stock, Value, Issued, Ending Balance
Preferred Stock, Value, Issued, Total
Preferred Stock, Value, Issued, Beginning Balance
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition
Stock-based compensation
APIC, Share-based Payment Arrangement, Increase for Cost Recognition, Total
Information pertaining to Pfizer, Inc.
Pfizer Inc [Member]
Pfizer Inc
Number of Asian markets.
Number of Asian Markets
Number of Asian markets
Counterparty Name [Domain]
Counterparty Name
Operating Lease, Liability
Present value of operating lease liabilities
Operating Lease, Liability, Total
Net Cash Provided by (Used in) Financing Activities
Net cash (used in) provided by financing activities
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value [Abstract]
Weighted average grant date fair value
Statement of Financial Position [Abstract]
Entity File Number
Entity File Number
Scenario [Domain]
Scenario
Statement of Cash Flows [Abstract]
Cash Equivalents, at Carrying Value [Abstract]
Cash Equivalents
Valuation Approach and Technique [Domain]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights
Common stock to be issued if warrants are exercised (in shares)
Line Of Credit Facility Current Borrowing Capacity
Line of Credit Facility, Current Borrowing Capacity
Proceeds from Issuance of Debt
Proceeds from debt
Statistical Measurement [Domain]
Statistical Measurement
Statement of Stockholders' Equity [Abstract]
Sale of Stock [Axis]
Sale of Stock
Amortization of debt discount related issuance costs and warrants
Amortization of Debt Discount (Premium)
Amortization of debt discount
Carrying value as of the balance sheet date of obligations incurred through that date and payable for research and development. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).
Accrued Research And Development Current
Accrued research and development
Common stock sales agreement shares unsold amount.
Common Stock Sales Agreement Shares Unsold Amount
Common stock sales agreement, shares unsold amount
Lease, Cost [Table Text Block]
Schedule of Operating Lease Expense
Accounting Standards Update 2020-10 [Member]
2020-10
Subsequent Events [Abstract]
Fair Value of Financial Instruments
Fair Value Disclosures [Text Block]
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Expirations in Period, Weighted Average Exercise Price
Weighted average exercise price, Expired
2014-09
Accounting Standards Update 2014-09 [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term
Weighted average contractual term, Exercisable
Proceeds from Stock Options Exercised
Proceeds from issuance of common stock upon exercise of options
Proceeds from Issuance of Common Stock
Proceeds from issuance of common stock upon financing, net
Long-Term Debt, Type [Axis]
Probability of Occurrence (periodic for each Milestone)
Probability Of Occurrence Periodic For Each Milestone [Member]
Probability of occurrence periodic for each milestone [Member]
Contingent consideration, measurement input
Business Combination, Contingent Consideration, Liability, Measurement Input
The amount of proceeds from first advance used to repay previous debt.
Proceeds From First Advance Used To Repay Previous Debt
First advance used to repay previous debt
Concentration Risk, Credit Risk, Policy [Policy Text Block]
Concentration of Credit Risk
Antidilutive Securities [Axis]
Antidilutive Securities
Line of Credit Facility, Maximum Borrowing Capacity
Maximum loan amount
Schedule of Stockholders' Equity Note, Warrants or Rights [Table Text Block]
Schedule of Warrant Activity
Preferred Stock, Par or Stated Value Per Share
Preferred stock, par value
Total
Business Combination, Recognized Identifiable Assets Acquired, Goodwill, and Liabilities Assumed, Net
Accounting policies.
Accounting Policies [Table]
Accounting Policies [Table]
Represents the information if the outstanding principle and advances under loan agreement exceeds fifty five million.
Outstanding Advances Under Loan Agreement Equals Or Exceeds Sixty Five Million [Member]
Outstanding principle and advances under the loans agreement exceeds 65 million
Credit Facility [Domain]
Subsequent Events [Text Block]
Subsequent Event
Weighted average common shares outstanding, diluted
Weighted Average Number of Shares Outstanding, Diluted
Weighted Average Number of Shares Outstanding, Diluted, Total
Credit Facility [Axis]
Share-Based Payment Arrangement, Nonvested Award, Excluding Option, Cost Not yet Recognized, Amount
Compensation cost not yet recognized related to unvested RSUs
Net Loss
Business Acquisition, Pro Forma Net Income (Loss)
Royalty Expense
Milestone payments or royalties
Development milestones.
Development Milestones
Development milestones
General and Administrative Expense [Member]
General and Administrative
Research and Development Arrangement, Contract to Perform for Others, Type [Domain]
Research and Development Arrangement, Contract to Perform for Others, Type
Share-Based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount
Unrecognized compensation cost related to non-vested stock options expected to be recognized
Probability of occurrence (cumulative through each Milestone)
Probability Of Occurrence Cumulative Through Each Milestone [Member]
Probability of occurrence cumulative through each milestone [Member].
Current Fiscal Year End Date
Current Fiscal Year End Date
Business combination purchase price allocated to goodwill deductible in number of years
Business Combination Purchase Price Allocated To Goodwill Deductible In Number Of Years
Business combination purchase price allocated to goodwill deductible in number of years.
Liability Class [Axis]
Two thousand nineteen shelf registration.
Two Thousand Nineteen Shelf Registration [Member]
2019 Shelf Registration
Depreciation
Depreciation
Depreciation, Total
Number of warrants (or share units) exercised during the current period.
Warrants Exercised In Period
Number of warrants exercised
The increase (decrease) during the reporting period in the value of prepaid expenses and other current assets not separately disclosed in the statement of cash flows, for example, deferred expenses, intangible assets, or income taxes.
Increase Decrease In Prepaid Expense And Other Assets Current
Prepaid expenses and other current assets
Accounts receivables standard payment term
Accounts Receivables Standard Payment Term
Accounts receivables standard payment term.
Other Assets, Noncurrent
Other assets
Other Assets, Noncurrent, Total
Accounting policies.
Accounting Policies [Line Items]
Accounting Policies [Line Items]
Entity Address, Address Line One
Entity Address, Address Line One
Represents information pertaining to the 2015 Equity Compensation Plan.
Two Thousand Fifteen Equity Compensation Plan [Member]
2015 Plan
Represents information pertaining to AXS-05.
Axs05 [Member]
AXS-05
Supplemental Cash Flow Information [Abstract]
Supplemental disclosures of cash flow information:
Tranche three sub tranche two.
Tranche Three Sub Tranche Two [Member]
Tranche Three Sub Tranche Two
Contingent Consideration Type [Domain]
December two thousand nineteen sales agreement.
December Two Thousand Nineteen Sales Agreement [Member]
December 2019 Sales Agreement
Income Tax Expense (Benefit)
Income tax benefit
Income Tax Expense (Benefit), Total
Proceeds from draw down
Proceeds from Long-Term Lines of Credit
Preferred Stock, Shares Issued
Preferred stock, shares issued
Preferred Stock, Shares Issued, Total
Payments to Acquire Property, Plant, and Equipment
Purchases of equipment
Payments to Acquire Property, Plant, and Equipment, Total
Jazz pharmaceuticals Plc.
Jazz Pharmaceuticals Plc [Member]
Jazz Pharmaceuticals Plc
Royalty Agreements
Royalty Agreements Disclosure [Text Block]
Royalty agreements disclosure text block
Line of Credit Facility [Table]
Line Of Credit Facility [Table]
Change in Accounting Principle, Accounting Standards Update, Adoption Date
Change in accounting principle, accounting standards update, adoption date
Represents the multiplier used for the cash pay interest under the debt instrument.
Debt Instrument Cash Pay Interest Multiplier
Cash pay interest multiplier
Stock Issued During Period, Shares, New Issues
Shares issued
Amount of accreted liability of final payment fee.
Debt Instrument Accreted Liability Of Final Payment Fee
Add: accreted liability of final payment fee
Fair value price of a single share of a number of saleable stocks of a company
Share Price Fair Value
Fair value share price
Number of reporting units
Number of Reporting Units
Total operating expenses
Costs and Expenses
Fair Value Hierarchy and NAV [Axis]
Share-Based Payment Arrangement [Policy Text Block]
Stock Based Compensation
Accrued Liabilities and Other Liabilities [Abstract]
Schedule of Research and Development Arrangement, Contract to Perform for Others [Table]
Schedule Of Research And Development Arrangement Contract To Perform For Others [Table]
Equity [Abstract]
Segment Reporting, Disclosure of Entity's Reportable Segments [Abstract]
Segment and Geographic Information
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Weighted average exercise price, Forfeited
Net equity impact of the value of new stock issued during the period. Includes shares issued in an initial public offering or a secondary public offering.
Stock Issued During Period Value New Issues Net
Proceeds from issuance of common stock, net
Loss from operations
Operating Income (Loss)
Loss from operations
Debt Instrument, Interest Rate, Stated Percentage
Base interest rate
Stock vested during period value restricted common stock award.
Stock Vested During Period Value Restricted Common Stock Award
Issuance of common stock upon vesting of RSUs
Lessee, operating lease, option to extend
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Nonvested, Number of Shares
Non-vested options outstanding
Share-based Compensation Arrangement by Share-based Payment Award, Options, Nonvested, Number of Shares, Beginning Balance
Share-based Compensation Arrangement by Share-based Payment Award, Options, Nonvested, Number of Shares, Ending Balance
Related Party [Domain]
Related Party
Additional Paid in Capital, Common Stock
Additional paid-in capital
Additional Paid in Capital, Common Stock, Beginning Balance
Additional Paid in Capital, Common Stock, Ending Balance
Tranche two sub tranche two.
Tranche Two Sub Tranche Two [Member]
Tranche Two Sub-Tranche Two
Scenario [Axis]
Scenario
Entity Filer Category
Entity Filer Category
Fair Value by Liability Class [Domain]
Entity Current Reporting Status
Entity Current Reporting Status
Other current assets
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Current Assets, Other
Inventories, net
Inventory, Net
Inventory, Net, Total
Prime Rate [Member]
Prime Rate
Inventory
Inventory Disclosure [Text Block]
Fair value of contingent consideration
Business Combination Consideration Fair Value of Contingent Consideration
Business combination consideration fair value of contingent consideration.
Stockholders' Equity Note Disclosure [Text Block]
Stockholders' Equity
Business Combination
Business Combinations [Abstract]
Total
Finite-Lived Intangible Assets, Net
Finite-Lived Intangible Assets, Net, Ending Balance
Finite-Lived Intangible Assets, Net, Beginning Balance
Stockholders' Equity Attributable to Parent
Ending balance
Beginning balance
Total stockholders’ equity
Investment Income, Net
Investment Income, Net, Total
Interest income (expense)
Probability weighted income approach
Valuation, Income Approach [Member]
Contingent Consideration
Commitments and Contingencies, Policy [Policy Text Block]
Percentage of aggregate amount of loan.
Debt Instrument Aggregate Amount Percentage
Percentage of aggregate amount of loan
Long-Term Debt, Maturity, Year Two
2024
The final payment fee to be paid under the debt arrangement as a percentage of aggregate amount of all term loan advances minus the aggregate amount of repayments made.
Debt Instrument Final Payment Fee Threshold Percentage Of Debt Outstanding
Percentage of final payment fee
Entity Tax Identification Number
Entity Tax Identification Number
Income Statement Location [Axis]
Income Statement Location
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period
Number of shares, Forfeited
Common stock, $0.0001 par value per share (150,000,000 shares authorized, 39,914,411 and 37,816,794 shares issued and outstanding at June 30, 2022 and December 31, 2021, respectively)
Common Stock, Value, Issued
Value of common stock
Common Stock, Value, Issued, Total
Common Stock, Value, Issued, Beginning Balance
Common Stock, Value, Issued, Ending Balance
Fair Value, Assets and Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Abstract]
Retained Earnings (Accumulated Deficit)
Accumulated deficit
Accumulated deficit
Retained Earnings (Accumulated Deficit), Total
Retained Earnings (Accumulated Deficit), Beginning Balance
Retained Earnings (Accumulated Deficit), Ending Balance
The minimum percentage of revenue should be achieved under the debt instrument.
Long Term Debt Additional Drawn Minimum Revenue Percent
Minimum product revenue percent
Equity Components [Axis]
Equity Components
Business combination, transaction costs
Business Combination, Acquisition Related Costs
Accounting Standards Update [Domain]
Accounting Standards Update
Cash and Cash Equivalents, Policy [Policy Text Block]
Cash Equivalents
Entity Emerging Growth Company
Entity Emerging Growth Company
Schedule of Business Acquisitions, by Acquisition [Table]
Operating expenses:
Operating Expenses [Abstract]
Goodwill [Line Items]
Stock vested during period shares restricted common stock award.
Stock Vested During Period Shares Restricted Common Stock Award
Issuance of common stock upon vesting of RSUs (in shares)
Represents the number of votes per share each holder of shares is entitled to.
Equity Instrument Voting Rights Per Share
Common stock, voting right per share
Revenue Recognition
Revenue [Policy Text Block]
Cost of product sales
Cost of product sales
Cost of Revenue
Cost of Revenue, Total
Lessee, Operating Lease, Liability, to be Paid [Abstract]
Investment, Name [Axis]
Investment, Name
Increase (Decrease) in Other Accounts Payable and Accrued Liabilities
Accrued expenses and other current liabilities
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Additional Disclosures [Abstract]
Weighted average contractual term
The minimum percentage of cash to be maintained under debt instruments.
Long Term Debt Additional Drawn Covenant Minimum Cash To Be Maintained As Security Percent
Minimum percentage of cash to be maintained as a security
Document Transition Report
Document Transition Report
Long-Term Debt, Maturity, Year Three
2025
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value
Weighted average grant date fair value, Granted
Commitments and Contingencies Disclosure [Text Block]
Commitments and Contingencies
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Weighted average exercise price, Exercised
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward]
Number of shares
Accounts receivables, net
Accounts Receivable, after Allowance for Credit Loss, Current
Accounts Receivable, after Allowance for Credit Loss, Current, Total
Entity Common Stock, Shares Outstanding
Entity Common Stock, Shares Outstanding
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Research And Development Arrangement Contract To Perform For Others [Line Items]
Amortization of final payment fee
Amortization of Debt Issuance Costs
Amortization of debt issuance costs
Accounts Payable and Other Accrued Liabilities, Current
Accrued expenses and other current liabilities
Total
Amount, after noncurrent portion of unamortized (discount) premium and debt issuance costs, of long-term debt. Includes, but not limited to, notes payable, bonds payable, debentures, mortgage loans and commercial paper. Excludes capital lease obligations.
Long Term Debt Current Net Of Noncurrent Debt Discount
Less: current portion of long-term debt
Net Income (Loss) Attributable to Parent
Net loss
Net loss
Lessee operating lease liability payments due after year four.
Lessee Operating Lease Liability Payments Due After Year Four
Thereafter
Operating Lease, Liability, Current
Operating lease liability, current portion
Initial Cash Payment Per Collaboration Agreement.
Initial Cash Payment Per Collaboration Agreement
Upfront cash payment
Additional Paid-in Capital [Member]
Additional Paid-in Capital
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Collaborative Arrangement and Arrangement Other than Collaborative
Represents the maximum reduction percentage of the royalty due as a result of required payments to third parties.
License Agreement Royalty Due Maximum Reduction Percentage As Result Of Required Payments To Third Parties
License agreement royalty, maximum reduction percent as a result of required third party payments
Schedule of Preliminary Purchase Consideration
Schedule of Business Acquisition of Preliminary Purchase Consideration [Table Text Block]
Schedule of business acquisition of preliminary purchase consideration.
Payment, Tax Withholding, Share-Based Payment Arrangement
Payments of tax withholdings on stock award
Unobservable input weighted average rate
Unobservable Input Weighted Average Rate
Unobservable input weighted average rate.
Schedule of Maturities of Long-Term Debt [Table Text Block]
Schedule of Principal Payments
Schedule of fair value measurements of contingent consideration recurring include significant unobservable inputs
Fair Value Measurement Inputs and Valuation Techniques [Table Text Block]
Entity Registrant Name
Entity Registrant Name
Total
Liabilities, Fair Value Disclosure
Cash and Cash Equivalents, at Carrying Value
Cash and cash equivalents
Cash and Cash Equivalents, at Carrying Value, Total
Cash and Cash Equivalents, at Carrying Value, Beginning Balance
Cash and Cash Equivalents, at Carrying Value, Ending Balance
Earnings Per Share [Text Block]
Net Loss per Common Share
Sales
Revenues
Revenues, Total
Share-Based Payment Arrangement, Noncash Expense
Stock-based compensation expense
Share-based Payment Arrangement, Noncash Expense, Total
Property, Plant and Equipment, Net
Equipment, net
Property, Plant and Equipment, Net, Total
Property, Plant and Equipment, Net, Beginning Balance
Property, Plant and Equipment, Net, Ending Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term
Weighted average contractual term, Vested and expected to vest
Award Type [Domain]
Award Type
Statement [Line Items]
Statement [Line Items]
Weighted average price at which warrants were exercised.
Warrants Exercised In Period Weighted Average Exercise Price
Exercised (in dollars per share)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price
Weighted average exercise price, Vested and expected to vest
Accounting Standards Update and Change in Accounting Principle [Abstract]
Recent Accounting Pronouncements
Title of 12(b) Security
Title of 12(b) Security
Gross Carrying Amount
Finite-Lived Intangible Assets, Gross
Finite-Lived Intangible Assets, Gross, Total
Period during which warrants are active, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.
Class Of Warrant Or Right Term
Term of warrants (in years)
Increase (Decrease) in Accounts Payable
Accounts payable
Increase (Decrease) in Accounts Payable, Total
Affiliated Entity [Member]
Antecip
Common Stock [Member]
Common Stock
Cost of product sales (excluding amortization and depreciation)
Cost of product sales (excluding amortization and depreciation)
Cost of Goods and Service, Excluding Depreciation, Depletion, and Amortization
Net Cash Provided by (Used in) Operating Activities [Abstract]
Cash flows from operating activities
Equity Component [Domain]
Equity Component
Product sales
Revenue
Revenue from Contract with Customer, Excluding Assessed Tax
Entity Address, State or Province
Entity Address, State or Province
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect
Net (decrease) increase in cash
Document Type
Document Type
Interest Paid, Excluding Capitalized Interest, Operating Activities
Interest paid
Schedule of Unaudited Pro Forma Summary Presents Consolidated Information
Business Acquisition, Pro Forma Information [Table Text Block]
Goodwill
Goodwill Disclosure [Text Block]
Adjustments to Additional paid-in capital Shares tendered for withholding taxes.
Adjustments To Additional Paid In Capital Shares Tendered For Withholding Taxes
Shares tendered for withholding taxes
Accounts Receivable, net
Receivables [Abstract]
Entity Shell Company
Entity Shell Company
Class of Warrant or Right, Outstanding
Number of warrants outstanding ending balance
Number of warrants outstanding beginning balance
Debt instrument, interest payment period.
Debt Instrument Interest Payment Period
Debt instrument, interest payment period
Inventories, net
Increase (Decrease) in Inventories
Increase (Decrease) in Inventories, Total
Share-Based Payment Arrangement, Expense
Stock-based compensation expense
Fair Value of Financial Instruments, Policy [Policy Text Block]
Fair Value of Financial Instruments
Inventory step-up fair value
Business Combination, Step-Up Inventory Fair Value
Business combination, step-up inventory fair value.
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair Value, Recurring and Nonrecurring [Table]
Loss Contingencies [Line Items]
Loss Contingencies [Line Items]
Accrued selling, general and administrative
Accrued Selling, General and Administrative Current
Accrued selling, general and administrative current.
Represents about term loan tranche three.
Term Loan2020 Tranche Three [Member]
Term loan 2020 tranche three
Security Exchange Name
Security Exchange Name
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Significant Accounting Policies [Text Block]
Summary of Significant Accounting Policies
Revenue Discount Rate Increases or Decreases by Approximately 1%
Revenue Discount Rate Increases or Decreases by One Percentage [Member]
Revenue discount rate increases or decreases by one percentage.
Net Cash Provided by (Used in) Operating Activities
Net cash used in operating activities
December two thousand nineteen and march two thousand twenty two sales agreement.
December Two Thousand Nineteen and March Two Thousand Twenty Two Sales Agreement [Member]
December 2019 and March 2022 Sales Agreement
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Expected vesting period for non-vested share-based compensation
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Weighted average contractual term, Outstanding
Fair Value, by Balance Sheet Grouping [Table]
Cash at settlement
Cash paid for business combination
Payments to Acquire Businesses, Gross
Commitments and Contingencies Disclosure [Abstract]
Prepayment Occurs on or After First Anniversary and Prior to Second Anniversary of First Amendment Closing Date
Debt instrument prepayment occurs on or after first anniversary and prior to second anniversary of first amendment closing date.
Debt Instrument Prepayment Occurs On Or After First Anniversary And Prior To Second Anniversary Of First Amendment Closing Date [Member]
Second amendment to loan and security agreement.
Second Amendment To Loan and Security Agreement [Member]
Second Amendment To Loan and Security Agreement
Operating Lease, Cost
Total operating lease expense
Interest Payable, Current
Accrued Interest
Restricted Stock Units (RSUs) [Member]
Restricted Stock Units
Lessee, Operating Lease, Liability, Maturity [Table Text Block]
Schedule of Future Minimum Lease Payments of Operating Leases
Net revenues
Business Acquisition, Pro Forma Revenue
Warrant [Member]
Warrants
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
Summary of Stock Option Activity
New Accounting Pronouncements, Policy [Policy Text Block]
Recent Accounting Pronouncements
Common Stock, Shares, Outstanding
Common stock, shares outstanding
Common Stock, Shares, Outstanding, Beginning Balance
Common Stock, Shares, Outstanding, Ending Balance
Business Acquisition [Line Items]
Cost of Product Sales
Cost of Goods and Service [Policy Text Block]
Work in process
Inventory, Work in Process, Gross
Accrued royalties
Accrued Royalties, Current
Level 2
Fair Value, Inputs, Level 2 [Member]
Term Loan 2020
Represents about term loan two thousand twenty.
Term Loan2020 [Member]
Revenue Discount rate
Measurement Input, Revenue Multiple [Member]
Net Cash Provided by (Used in) Investing Activities [Abstract]
Cash flows from investing activities
Schedule of Finite Lived Intangible Assets Future Amortization Expense
Schedule of Finite-Lived Intangible Assets, Future Amortization Expense [Table Text Block]
Common Stock, Shares, Issued
Balance (in shares)
Balance (in shares)
Common stock, shares issued
Number of common shares
Common Stock, Shares, Issued, Total
Variable Rate [Domain]
Variable Rate
Minimum
Minimum
Represents the number of license agreements the Company has entered into.
Number Of License Agreements
Number of exclusive license agreements
Lessee, Leases [Policy Text Block]
Leases
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Weighted average exercise price, Exercisable
Accounting Standards Update [Axis]
Accounting Standards Update
Debt Instrument [Axis]
Debt Instrument
Stockholders' Equity Attributable to Parent [Abstract]
Stockholders’ equity:
Counterparty Name [Axis]
Counterparty Name
Entity Address, Address Line Two
Entity Address, Address Line Two
Foreign Currency Transactions and Translations Policy [Policy Text Block]
Foreign Currency Translation
Revenues [Abstract]
Number of days to achieve first milestone following such date.
Threshold Days To Achieve First Milestone
Period to achieve first milestone
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value
Weighted average grant date fair value, Forfeited
Discount Rate Increases or Decreases by Approximately 1%
Discount Rate Increases or Decreases by One Percentage [Member]
Discount rate increases or decreases by one percentage.
Intangible asset amortization
Amortization of intangible asset
Amortization of Intangible Assets
Represents the percentage of net sales of products containing the licensed products, due to licensor as a royalty.
License Agreement Royalty Due Percentage Of Net Sales
License agreement royalty as a percent of net sales
Award Type [Axis]
Award Type
Total
Cash and contingent consideration
Business Combination, Consideration Transferred
Loss Contingencies [Table]
Loss Contingencies [Table]
Research and Development Expense
Research and development
Research and development expense recognized
Research and Development Expense, Total
Lessee, Operating Lease, Liability, to be Paid
Total lease payments
Number of shares of stock issued during the period pursuant to a financing arrangement.
Stock Issued During Period Shares Financing
Issuance of common stock upon financing (in shares)
Lessee, Operating Lease, Term of Contract
Lease term
Entity Central Index Key
Entity Central Index Key
Contingent consideration liability, non-current
Contingent consideration, non-current
Business Combination, Contingent Consideration, Liability, Noncurrent
Represents information pertaining to AXS-04.
Axs04 [Member]
AXS-04
Represents the information pertaining to AXS-05 and AXS-07.
Axs05 And Axs07 [Member]
AXS-05 and AXS-07
Accounting Policies [Abstract]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Abstract]
Measurement Frequency [Axis]
Interest Expense, Debt, Excluding Amortization
Interest expense
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant
Shares available for future grant
Threshold period of specified consecutive trading days within which the volume weighted average price of company's common stock.
Class Of Warrants Or Rights Weighted Average Price Trading Days
Trading days
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value
Aggregate intrinsic value, Vested and expected to vest
Sunosi.
Sunosi [Member]
Sunosi
Accrued contingent consideration, current
Contingent consideration, current
Business Combination, Contingent Consideration, Liability, Current
Fair value of inventory
Fair Value Of Inventory
Fair value of inventory.
Measurement Input Type [Domain]
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Weighted average exercise price, Outstanding, ending balance
Weighted average exercise price, Outstanding, beginning balance
Research and Development Expense [Member]
Research and Development
Forecast [Member]
Forecast
Right-of-Use Asset Obtained in Exchange for Operating Lease Liability
Operating lease right-of-use asset obtained in exchange for operating lease liability
Business acquisition purchase price allocation goodwill expected tax deductible period
Business Acquisition Purchase Price Allocation Goodwill Expected Tax Deductible Period
Business acquisition purchase price allocation goodwill expected tax deductible period.
Retained Earnings [Member]
Accumulated Deficit
Measurement Input Type [Axis]
Effective Income Tax Rate Reconciliation, Percent
Effective tax rate
Effective Income Tax Rate Reconciliation, Percent, Total
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]
Schedule of Goodwill [Table]
Research and Development Arrangement, Contract to Perform for Others, Type [Axis]
Research and Development Arrangement, Contract to Perform for Others, Type
Goodwill from Sunosi Acquisition
Goodwill, Acquired During Period
Entity Interactive Data Current
Entity Interactive Data Current
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number
Number of shares, Vested and expected to vest
Supplemental non-cash investing activities:
Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract]
The minimum percentage of cash to be maintained as security following the market capitalization conditions under the debt instruments.
Long Term Debt Additional Drawn Covenant Minimum Cash To Be Maintained As Security With Market Capitalization Covenant Percent
Minimum percentage of cash to be maintained as a security following market capitalization condition
Lessee, Operating Lease, Liability, to be Paid, Year One
2023
Local Phone Number
Local Phone Number
Schedule of Preliminary Allocation of Fair Value
Schedule of Recognized Identified Assets Acquired and Liabilities Assumed [Table Text Block]
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
Computation of Basic and Diluted Net Loss per Common Share
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period
Vesting period
Debt Disclosure [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number
Number of shares, Exercisable
Lessee, Operating Lease, Description
Lessee, operating lease, description
Warrants and Rights Note Disclosure [Abstract]
Lender Name [Axis]
Lessee, operating lease, existence of option to extend [true false]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Number of shares, Granted
Schedule of fair value of the contingent consideration remeasured
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block]
Fair Value Measurement Inputs and Valuation Techniques [Abstract]
Milestone dates
Milestone Dates [Member]
Milestone dates [Member].
Income Statement Location [Domain]
Income Statement Location
Represents the information if the outstanding principle and advances under loan agreement exceeds fifty five million.
Outstanding Advances Under Loan Agreement Equals Or Exceeds Fifty Five Million [Member]
Outstanding principle and advances under the loans agreement exceeds 55 million
Long-Term Debt, Maturity, Year One
2023
Selling, General and Administrative Expenses
Selling, General and Administrative Expenses [Member]
Equipment, net
Property, Plant and Equipment [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number
Number of shares, Outstanding, ending balance
Number of shares, Outstanding, beginning balance
Long-Term Debt
Outstanding amount
Long-term Debt, Total
Line of Credit Facility, Remaining Borrowing Capacity
Remaining credit facility to be drawn
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Inventory Disclosure [Abstract]
Contingent Consideration by Type [Axis]
An underwritten sale of stock.
Underwritten Public Offering [Member]
Underwritten Public Offering
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Number of shares, Outstanding, ending balance
Number of shares, Outstanding, beginning balance
Share Price
Share Price
Share price
Upfront payment.
Upfront Payment
Upfront payment
Schedule of fair value of financial instruments measured on a recurring basis
Fair Value, Liabilities Measured on Recurring Basis [Table Text Block]
Debt Instrument, Name [Domain]
Debt Instrument, Name
Document Fiscal Year Focus
Document Fiscal Year Focus
Balance at December 31, 2021
Net Book Value at June 30, 2022
Intangible asset, net
Intangible Assets, Net (Excluding Goodwill)
Intangible Assets, Net (Excluding Goodwill), Total
Payment of debt issuance costs
Payments of Debt Issuance Costs
Lessee, Operating Lease, Liability, to be Paid, Year Two
2024
Net loss per common share, basic
Earnings Per Share, Basic
Earnings Per Share, Basic, Total
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract]
Weighted average exercise price
Assets [Abstract]
Assets
Schedule of Long-Term Debt Instruments [Table Text Block]
Schedule of Outstanding Debt and Unamortized Debt Discount Balances
Prepaid Expense and Other Assets, Current
Prepaid and other current assets
Represents the prepayment of debt occurring on or after the first anniversary and prior to the second anniversary of the Closing Date.
Debt Instrument Prepayment Occurs On Or After First Anniversary And Prior To Second Anniversary Of Closing Date [Member]
Prepayment Occurs on or After First Anniversary and Prior to Second Anniversary of the Closing Date
Fair value of contingent consideration in a business combination
Fair Value Of Contingent Consideration In A Business Combination
Fair value of contingent consideration in a business combination.
Change in operating lease liability.
Change In Operating Lease Liability
Change in operating lease liability
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward]
Number of shares
Liabilities and Equity [Abstract]
Liabilities and stockholders’ equity
Total
Inventory, Gross
Equipment, net
Property, Plant and Equipment, Policy [Policy Text Block]
Antidilutive Securities, Name [Domain]
Antidilutive Securities, Name
Initial estimate
Fair Value Measurement With Unobservable Inputs Reconciliations Recurring Basis Liability Initial Estimate
Fair value measurement with unobservable inputs reconciliations recurring basis liability initial estimate.
Valuation Approach and Technique [Axis]
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest
Net loss
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total
Represents about term loan tranche five.
Term Loan2020 Tranche Five [Member]
Term loan 2020 tranche five
Disclosure of accounting policy for significant risks and uncertainties.
Significant Risks And Uncertainties Policy Policy [Text Block]
Significant Risks And Uncertainties
Assets, Current [Abstract]
Current assets:
2025
Finite-Lived Intangible Asset, Expected Amortization, Year Four
2023
Finite-Lived Intangible Asset, Expected Amortization, Year Two
Class of Warrant or Right, Exercise Price of Warrants or Rights
Weighted average exercise price, Ending balance
Weighted average exercise price, Beginning balance
Exercise price of warrants (in dollars per share)
Long term debt upon milestone achievement amount
Long Term Debt upon Milestone Achievement Amount
Long term debt upon milestone achievement amount.
Schedule of Goodwill
Schedule of Goodwill [Table Text Block]
Fair Value Hierarchy and NAV [Domain]
Measurement Frequency [Domain]
Issuance of warrants upon debt financing
Warrants issued during period debt financing.
Warrants Issued During Period Debt Financing
Increase (Decrease) in Operating Capital [Abstract]
Changes in operating assets and liabilities:
Number of warrants (or share units) issued during the current period.
Warrants Issued In Period
Number of warrants issued
Accrued sales discounts, rebates and allowances
Accrued Sales Commission, Current
Cover [Abstract]
Product and Service [Domain]
Product and Service
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period
Number of shares, Vested
Finished goods
Inventory, Finished Goods, Gross
Goodwill impairment
Goodwill, Impairment Loss
Represents the consecutive number of trading days to determine the weighted average price per share of ordinary shares.
Consecutive Trading Days
Prior trading days
Cost of Product Sales
Cost of Revenue [Abstract]
Liabilities, Current [Abstract]
Current liabilities:
Maximum
Maximum
Period of time, after the first commercial sale of the applicable product, the license agreement is valid, in PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.
License Agreement Term
License agreement term, from first commercial sale
Schedule of Interest and Amortization Expense for Final Payment Fee and Debt Discount
Schedule of Interest and Amortization Expense for Final Payment Fee and Debt Discount [Table Text Block]
Schedule of interest and amortization expense for final payment fee and debt discount.
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
Schedule of Stock-Based Compensation Expense Recognized
Net Cash Provided by (Used in) Investing Activities
Net cash used in investing activities
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table]
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period
Issuance of common stock upon exercise of options (in shares)
Number of shares, Exercised
Schedule of Inventory
Schedule of Inventory, Current [Table Text Block]
Level 3
Fair Value, Inputs, Level 3 [Member]
Use of Estimates, Policy [Policy Text Block]
Use of Estimates
Debt Instrument, Basis Spread on Variable Rate
Interest rate basis
Hercules Capital Inc.
Hercules Capital Inc [Member]
Hercules Capital Inc
Cash Equivalents, at Carrying Value
Cash Equivalents
Cash Equivalents, at Carrying Value, Total
Represents the prepayment of debt occurring after the second anniversary and prior to the third anniversary of the Closing Date.
Debt Instrument Prepayment Occurs On Or After Second Anniversary And Prior To Third Anniversary Of Closing Date [Member]
Prepayment Occurs on or After Second Anniversary and Prior to Third Anniversary of Closing Date
Long-Term Debt, Maturity, Remainder of Fiscal Year
2022
Stock Issued During Period, Value, Stock Options Exercised
Issuance of common stock upon exercise of options
Segment Reporting, Policy [Policy Text Block]
Segment and Geographic Information
2026
Finite-Lived Intangible Asset, Expected Amortization, Year Five
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Aggregate Intrinsic Value
Aggregate intrinsic value, Exercisable
Property, Plant and Equipment, Useful Life
Estimated useful life
Long-Term Debt, Gross
Total Outstanding Debt
Total principal payments outstanding
2024
Finite-Lived Intangible Asset, Expected Amortization, Year Three
Represents about term loan tranche four.
Term Loan2020 Tranche Four [Member]
Term loan 2020 tranche four
Common Stock, Shares Authorized
Common stock, shares authorized
March Two Thousand Twenty Two Sales Agreement [Member]
March Two Thousand Twenty Two Sales Agreement [Member]
March 2022 Sales Agreement
Represents the prepayment penalty percentage on principal amount of debt.
Debt Instrument Prepayment Penalty Percentage
Percentage of prepayment penalty
Trading Symbol
Trading Symbol
The minimum amount of cash should be maintained as first priority security interest under the terms of debt instrument.
Long Term Debt Additional Drawn Covenant Minimum Cash As Security Interest
Minimum cash to be maintain as a first priority security interest
Selling, general and administrative
Selling, General and Administrative Expense
Selling, General and Administrative Expense, Total
Amortization of operating lease right-of-use asset
Term loan.
Term Loan [Member]
Term Loan
Tranche two sub tranche three.
Tranche Two Sub Tranche Three [Member]
Tranche Two Sub-Tranche Three
Accounts Payable, Current
Accounts payable
Accounts Payable, Current, Total
Plan Name [Axis]
Plan Name
This member stands for Term Loan 2019.
Term Loan2019 [Member]
2019 Term Loan
Common Stock, Par or Stated Value Per Share
Common stock, par value
Share-Based Payment Arrangement, Restricted Stock and Restricted Stock Unit, Activity [Table Text Block]
Schedule of RSU Activity
Fair value of sample inventory
Fair Value Of Sample Inventory
Fair value of sample inventory.
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period
Number of shares, Granted
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Weighted average exercise price, Granted
Developed technology
Business Combination Recognized Identifiable Assets Acquired and Liabilities Assumed Current Assets Developed Technology
Business combination recognized identifiable assets acquired and liabilities assumed current assets developed technology.
Long-Term Debt [Text Block]
Loan and Security Agreement
Long-Term Debt, Type [Domain]
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Antidilutive securities
Other assets
Increase (Decrease) in Other Noncurrent Assets