Entity Address, City or Town
Entity Address, City or Town
Schedule Of Loss Before Income Taxes Effective Income Tax Rate
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
Fair Value Disclosures [Abstract]
Earnings Per Share [Abstract]
Fair Value, Inputs, Level 1 [Member]
Level 1
Schedule of Accrued Expenses
Schedule of Accrued Liabilities [Table Text Block]
Fair value of common stock
Common Stock Fair Value
Fair value of issued nonredeemable common stock (or common stock redeemable solely at the option of the issuer). This item includes treasury stock repurchased by the entity. Note: elements for number of nonredeemable common shares, par value and other disclosure concepts are in another section within stockholders' equity.
Proceeds from issuance of common stock, gross
Stock Issued During Period, Value, New Issues
Research and Development Costs
Research and Development Expense, Policy [Policy Text Block]
Cash flows from financing activities
Net Cash Provided by (Used in) Financing Activities [Abstract]
Weighted average contractual term
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Outstanding, Weighted Average Remaining Contractual Terms
License Agreement
License Agreement Terms [Member]
License Agreements
Amendment Flag
Amendment Flag
Business combination, non-operating assets, net of liabilities.
Business Combination, Non-Operating Assets, Net Of Liabilities
Less: non-operating assets, net of liabilities
Less: non-operating assets, net of liabilities
2026
Long-Term Debt, Maturity, Year Four
Subsequent Event Type [Domain]
Research and Development [Abstract]
Finite-Lived Intangible Assets, Accumulated Amortization
Amortization Expense
Term loan two thousand and twenty two warrants.
Term Loan Two Thousand and Twenty Two Warrants [Member]
2022 warrants
Goodwill, Total
Goodwill
Goodwill
Balance at December 31,2021
Goodwill, beginning balance
Goodwill, ending balance
Right-of-use asset - operating lease
Operating Lease, Right-of-Use Asset
Schedule of Finite-Lived Intangible Assets [Table Text Block]
Schedule of Net Book Value of our Intangible Asset
Number of customers.
Number Of Customers
Number of customers
Document Quarterly Report
Document Quarterly Report
Less imputed interest
Lessee, Operating Lease, Liability, Undiscounted Excess Amount
Basic and Diluted Net Loss per Common Share
Earnings Per Share, Policy [Policy Text Block]
Debt instrument prepayment occurring prior to february one two thousand twenty four.
Debt Instrument Prepayment Occurring Prior to February One Two Thousand Twenty Four [Member]
Prepayment Occurs Prior to February 1, 2024
Percentage of discount rate intangible asset measurement input.
Percentage of Discount Rate Intangible Asset Measurement Input
Percentage of discount rate intangible asset measurement input
Statement [Table]
Statement [Table]
Operating lease liability, long-term
Operating Lease, Liability, Noncurrent
Unrecognized Tax Benefits that Would Impact Effective Tax Rate
Unrecognized tax benefits
Common stock sales agreement, authorized amount
Common Stock Sales Agreement Authorized Amount
The authorized amount under a common stock sales agreement.
Inventory current and noncurrent.
Inventory Current and Noncurrent
Total
Number of operating segments
Number of Operating Segments
Preferred Stock, Shares Outstanding, Ending Balance
Preferred Stock, Shares Outstanding, Beginning Balance
Preferred stock, shares outstanding
Preferred Stock, Shares Outstanding
Business Acquisition [Axis]
Weighted average grant date fair value, Outstanding, beginning balance
Weighted average grant date fair value, Outstanding, ending balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value
Weighted average grant date fair value, Vested
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value
Debt instrument maturity, month and year
Debt Instruments Maturity Month And Year
Debt instruments maturity, month and year.
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Inventory
Inventory fair value step-up on inventory acquired
Inventory
Term loan 2020 tranche one
Term Loan2020 Tranche One [Member]
Represents about term loan tranche one.
2020 warrants
Line Of Credit Facility [Line Items]
Line of Credit Facility [Line Items]
Increase (Decrease) in Income Taxes
Provision for income taxes
Business Combination Disclosure [Text Block]
Business Combination
Product and Service
Product and Service [Axis]
Employee Stock Purchase Plan
Employee Stock [Member]
Debt Issuance Costs
Debt, Policy [Policy Text Block]
Fair value of contingent consideration
Contingent Consideration Liability, Total
Contingent consideration
Contingent consideration liability
Finite-Lived Intangible Asset, Useful Life
Intangible assets, Estimated period of benefit
Remaining Weighted-Average Useful Life
Leerink
Leerink [Member]
Leerink.
Employee-related Liabilities, Current, Total
Accrued compensation
Employee-related Liabilities, Current
Trade Receivables.
Trade Receivables
Number of late-stage candidates not yet approved in Company's product candidate portfolio
Number Of Late Stage Product Candidates
Represents the number of late-stage candidates included in the Company's product candidate portfolio.
Stock Options
Share-Based Payment Arrangement, Option [Member]
Concentration Risk Type [Axis]
Operating lease, remaining lease term
Operating Lease, Weighted Average Remaining Lease Term
Total liabilities and stockholders’ equity
Liabilities and Equity
Inventory
Inventory, Policy [Policy Text Block]
Plan Name
Plan Name [Domain]
Line of Credit Facility, Lender [Domain]
Non-current inventory and other assets
Debt instrument prepayment occurring on or after february one two thousand twenty four but prior to february one two thousand twenty five.
Debt Instrument Prepayment Occurring On or After February One Two Thousand Twenty Four But Prior to February One Two Thousand Twenty Five [Member]
Prepayment Occurs On or After February 1, 2024 but Prior to February 1, 2025
Inventory, Raw Materials, Gross
Raw materials
Warrant liability
Fair Value Of Warrant Liability
Fair value of warrant liability.
Measurement Input, Discount Rate [Member]
Measurement Input Discount Rate
Entity Incorporation, State or Country Code
Entity Incorporation, State or Country Code
Income Statement [Abstract]
Ex-U.S. Market Sales
Non-US [Member]
Tranche Two Sub Tranche One [Member]
Tranche two sub tranche one.
Tranche Two Sub Tranche One
Nature of Business and Basis of Presentation
Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block]
Goodwill [Abstract].
Goodwill [Abstract]
Rule 10b5-1 Arrangement Terminated
Rule 10b5-1 Arrangement Terminated
Final payment fee
Extinguishment Of Debt Fee Amount
The final payment fee at extinguishment of debt.
Sale of Stock
Sale of Stock [Domain]
Contingent consideration [Member].
Contingent Consideration [Member]
Contingent consideration
Total current liabilities
Liabilities, Current
Third amendment to loan and security agreement.
Third Amendment To Loan and Security Agreement [Member]
Third Amendment To Loan and Security Agreement
Business Combinations Policy [Policy Text Block]
Business Combination
Future milestone payments
Collaboration Arrangement Future Potential Payments
The amount of future payments payable under the collaboration arrangement.
Minimum amount of market capital to be maintained
Long Term Debt Additional Drawn Covenant Minimum Market Capitalization Amount
The minimum amount of market capital to be maintained under debt instruments.
2026
Lessee, Operating Lease, Liability, to be Paid, Year Three
Long-Term Debt, Maturity, Year Five
2027
Business Acquisition, Acquiree [Domain]
Fair Value, Recurring [Member]
Accounts Receivable, Allowance for Credit Loss, Beginning Balance
Accounts Receivable, Allowance for Credit Loss, Ending Balance
Accounts Receivable, Allowance for Credit Loss
Accounts receivable, Allowance for credit loss
Accrued Expenses and Other Current Liabilities
Accounts Payable and Accrued Liabilities Disclosure [Text Block]
Income Taxes
Income Tax, Policy [Policy Text Block]
Adjustments to reconcile net loss to net cash used in operating activities:
Adjustments, Noncash Items, to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract]
Preferred stock, shares authorized
Preferred Stock, Shares Authorized
Long term debt different from remaining drawn covenant minimum cash flow percentage.
Long Term Debt Different From Remaining Drawn Covenant Minimum Cash Flow Percentage
Minimum different from remaining percentage of cash flow
Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table]
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table]
Operating lease, discount rate
Operating Lease, Weighted Average Discount Rate, Percent
Fourth Amendment To Loan and Security Agreement
Fourth Amendment To Loan and Security Agreement [Member]
Fourth amendment to loan and security agreement.
Investment, Name
Investment, Name [Domain]
Variable Rate
Variable Rate [Axis]
Entity Small Business
Entity Small Business
Cash at end of period
Cash at beginning of period
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Total
Collaborative Arrangement and Arrangement Other than Collaborative
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Fair Value Measurement Inputs and Valuation Techniques [Table]
Fair value
Fair Value Of Warrants
The fair value of outstanding warrants.
Term loan advances other than tranche one A.
Term Loan Advances Other Than Tranche One A [Member]
Term Loan Advances Other Than Tranche 1A
Revenue milestones
Revenue Milestones
Revenue milestones.
Intangible Assets Disclosure [Text Block]
Intangible Asset
Prepayment Occurs Prior to First Anniversary of Closing Date
Debt Instrument Prepayment Occurring Prior To First Anniversary Of Closing Date [Member]
Represents the prepayment of debt occurring prior to first anniversary of closing date.
AXS-02
Axs02 [Member]
Represents information pertaining to AXS-02.
Total current assets
Assets, Current
Aggregate intrinsic value
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest [Abstract]
Lessee, Operating Lease, Liability, to be Paid, Remainder of Fiscal Year
2023
Intangible Assets Abstract.
Intangible Assets [Abstract]
Weighted Average Number of Shares Outstanding, Basic, Total
Weighted Average Number of Shares Outstanding, Basic
Weighted average common shares outstanding, basic
Adjustment to fair value
Loss (Gain) in fair value of contingent consideration
Change in fair value of contingent considerations.
Change In Fair Value Of Contingent Considerations
Change in fair value of contingent consideration
August 2022 Sales Agreement
August Two Thousand Twenty Two Sales Agreement [Member]
August two thousand twenty two sales agreement.
City Area Code
City Area Code
Aggregate intrinsic value, Outstanding
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value
Rule 10b5-1 Arrangement Adopted
Rule 10b5-1 Arrangement Adopted
Number of shares, Forfeited
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period
Tranche Three Sub Tranche One
Tranche Three Sub Tranche One [Member]
Tranche three sub tranche one.
Issued (in dollars per share)
Warrants Issued In Period Weighted Average Exercise Price
Weighted average price at which warrants were issued.
Prior period adjustments for product sales resulting from changes in estimates.
Prior Period Adjustments For Product Sales Resulting From Changes in Estimates
Prior period adjustments for product sales resulting from changes in estimates
Total liabilities
Liabilities
Document Period End Date
Document Period End Date
Cash paid for common stock issuance costs
Payments of Stock Issuance Costs
Sunosi and Auvelity
Sunosi and Auvelity [Member]
Sunosi and Auvelity.
Weighted average grant date fair value
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value
Lease term
Lessee, Operating Lease, Renewal Term
Concentration of Credit Risk
Risks and Uncertainties [Abstract]
Finite-Lived Intangible Asset, Expected Amortization, Year One
2024
Statistical Measurement
Statistical Measurement [Axis]
Income Taxes
Effective Income Tax Rate Reconciliation, Percent [Abstract]
Underwriting discounts and commissions
Underwriting Discounts And Commissions
Underwriting discounts and commissions.
Adoption Date
Trd Arr Adoption Date
Trd Arr Adoption Date.
Subsequent Event [Line Items]
Related Party
Related Party [Axis]
Total assets
Assets
Other offering costs
Other Offering Costs
Other offering costs.
Previously Reported [Member]
Previoiusly Reported
Common stock sales agreement, commission percentage
Common Stock Sales Agreement Commission Percentage
The commission percentage paid under a common stock sales agreement.
Revenue, Performance Obligation, Description of Payment Terms
Payment terms
Loan payable, long-term
Loan payable, long-term
Long-Term Debt, Excluding Current Maturities
License Agreements
License Agreements Disclosure [Text Block]
The entire disclosure for license agreements.
Earnings Per Share, Diluted, Total
Earnings Per Share, Diluted
Net loss per common share, diluted
Accounts Receivable [Policy Text Block]
Accounts Receivable, net
Number of shares, Expired
Share Based Compensation Arrangement By Share Based Payment Award Options Expired In Period
Share based compensation arrangement by share based payment award options expired in period.
Schedule of Potentially Dilutive Securities
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Less: unamortized debt discount, long-term
Debt Instrument, Unamortized Discount, Noncurrent
Ending Balance (Level 3)
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability Value
Beginning Balance
Fair value of contingent consideration
Fair Value Measurement Inputs and Valuation Techniques [Line Items]
Entity Address, Postal Zip Code
Entity Address, Postal Zip Code
Revision of Prior Period [Axis]
Document Fiscal Period Focus
Document Fiscal Period Focus
Number of financial institutions that hold the Company's cash
Number Of Financial Institutions Holding Deposits
Represents the number of financial institutions holding the Company's cash.
Issuance of common stock upon financing
Stock Issued During Period Value Financing
Value of stock issued pursuant to a financing arrangement during the period.
Business combination, recognized identifiable assets acquired and liabilities assumed, current liabilities, accrued expenses and other current liabilities.
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Current Liabilities, Accrued Expenses and Other Current Liabilities
Accrued expenses and other current liabilities
Increase (Decrease) in Accounts Receivable
Accounts receivable, net
Preferred stock, $0.0001 par value per share (10,000,000 shares authorized, none issued and outstanding at June 30, 2023 and December 31, 2022, respectively)
Preferred Stock, Value, Issued, Beginning Balance
Preferred Stock, Value, Issued, Total
Preferred Stock, Value, Issued, Ending Balance
Preferred Stock, Value, Issued
APIC, Share-based Payment Arrangement, Increase for Cost Recognition, Total
Stock-based compensation
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition
Pfizer Inc
Pfizer Inc [Member]
Information pertaining to Pfizer, Inc.
Number of Asian markets
Number of Asian Markets
Number of Asian markets.
Counterparty Name
Counterparty Name [Domain]
Operating Lease, Liability, Total
Present value of operating lease liabilities
Operating Lease, Liability
Net cash provided by financing activities
Net Cash Provided by (Used in) Financing Activities
Weighted average grant date fair value
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value [Abstract]
Product Sales Member
Product Sales Member
Product Sales
Statement of Financial Position [Abstract]
Entity File Number
Entity File Number
Scenario
Scenario [Domain]
Statement of Cash Flows [Abstract]
Cash Equivalents
Cash Equivalents, at Carrying Value [Abstract]
Valuation Approach and Technique [Domain]
Common stock to be issued if warrants are exercised (in shares)
Class of Warrant or Right, Number of Securities Called by Warrants or Rights
Line of Credit Facility, Current Borrowing Capacity
Line Of Credit Facility Current Borrowing Capacity
Geographical [Domain]
Statistical Measurement
Statistical Measurement [Domain]
Statement of Stockholders' Equity [Abstract]
Sale of Stock
Sale of Stock [Axis]
Amortization of debt discount
Amortization of Debt Discount (Premium)
Amortization of debt discount related issuance costs and warrants
Purchase price of common stock percent
Share-Based Compensation Arrangement by Share-Based Payment Award, Purchase Price of Common Stock, Percent
Accrued research and development
Accrued Research And Development Current
Carrying value as of the balance sheet date of obligations incurred through that date and payable for research and development. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).
Common stock sales agreement, shares unsold amount
Common Stock Sales Agreement Shares Unsold Amount
Common stock sales agreement shares unsold amount.
License Agreements.
License Agreements [Policy Text Block]
License Agreements
Schedule of Operating Lease Expense
Lease, Cost [Table Text Block]
Trading Arrangements, by Individual
Deferred Compensation Arrangement with Individual, Excluding Share-Based Payments and Postretirement Benefits [Line Items]
Auvelity.
Auvelity [Member]
Auvelity
Subsequent Events [Abstract]
Fair Value Disclosures [Text Block]
Fair Value of Financial Instruments
Weighted average exercise price, Expired
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Expirations in Period, Weighted Average Exercise Price
Weighted average contractual term, Exercisable
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term
Underwriters exercised their option
Proceeds from issuance of common stock upon exercise of options
Proceeds from Stock Options Exercised
Proceeds from issuance of common stock upon financing
Proceeds from Issuance of Common Stock
Proceeds from Issuance of Common Stock
Long-Term Debt, Type [Axis]
Probability of occurrence periodic for each milestone [Member]
Probability Of Occurrence Periodic For Each Milestone [Member]
Probability of Occurrence (periodic for each Milestone)
Business Combination, Contingent Consideration, Liability, Measurement Input
Contingent consideration, measurement input
Concentration Risk, Credit Risk, Policy [Policy Text Block]
Concentration of Risk
Non-current inventory and other assets
Non Current Inventory and Other Assets
Non-current inventory and other assets
Antidilutive Securities
Antidilutive Securities [Axis]
Maximum loan amount
Line of Credit Facility, Maximum Borrowing Capacity
Schedule of Warrant Activity
Schedule of Stockholders' Equity Note, Warrants or Rights [Table Text Block]
Preferred stock, par value
Preferred Stock, Par or Stated Value Per Share
Finite-Lived Intangible Asset, Expected Amortization, Remainder of Fiscal Year
2023
Customer Two.
Customer Two [Member]
Customer Two
Lessee, Lease, Description [Line Items]
Business Combination, Recognized Identifiable Assets Acquired, Goodwill, and Liabilities Assumed, Net
Total
Accounting Policies [Table]
Accounting Policies [Table]
Accounting policies.
Outstanding principle and advances under the loans agreement exceeds 65 million
Outstanding Advances Under Loan Agreement Equals Or Exceeds Sixty Five Million [Member]
Represents the information if the outstanding principle and advances under loan agreement exceeds fifty five million.
Credit Facility [Domain]
Royalty Revenue
Royalty Revenue
Royalty revenue
Subsequent Events [Text Block]
Subsequent Events
Weighted Average Number of Shares Outstanding, Diluted, Total
Weighted Average Number of Shares Outstanding, Diluted
Weighted average common shares outstanding, diluted
Loans, Notes, Trade and Other Receivables Disclosure [Text Block]
Accounts Receivable, net
Credit Facility [Axis]
Compensation cost not yet recognized related to unvested RSUs
Share-Based Payment Arrangement, Nonvested Award, Excluding Option, Cost Not yet Recognized, Amount
Business Acquisition, Pro Forma Net Income (Loss)
Net Loss
Milestone payments or royalties
Royalty Expense
Mtrl Terms Of Trd Arr2 [Text Block]
Mtrl Terms Of Trd Arr2
Development milestones
Development Milestones
Development milestones.
Selling General and Administrative
General and Administrative Expense [Member]
Research and Development Arrangement, Contract to Perform for Others, Type
Research and Development Arrangement, Contract to Perform for Others, Type [Domain]
Unrecognized compensation cost related to non-vested stock options expected to be recognized
Share-Based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount
Name
Trd Arr Ind Name
Trd Arr Ind Name.
Probability of occurrence cumulative through each milestone [Member].
Probability Of Occurrence Cumulative Through Each Milestone [Member]
Probability of occurrence (cumulative through each Milestone)
Current Fiscal Year End Date
Current Fiscal Year End Date
Business combination purchase price allocated to goodwill deductible in number of years.
Business Combination Purchase Price Allocated To Goodwill Deductible In Number Of Years
Business combination purchase price allocated to goodwill deductible in number of years
Liability Class [Axis]
2019 Shelf Registration
Two Thousand Nineteen Shelf Registration [Member]
Two thousand nineteen shelf registration.
Depreciation, Total
Depreciation
Depreciation
Number of warrants exercised
Warrants Exercised In Period
Number of warrants (or share units) exercised during the current period.
Prepaid expenses and other current assets
Increase Decrease In Prepaid Expense And Other Assets Current
The increase (decrease) during the reporting period in the value of prepaid expenses and other current assets not separately disclosed in the statement of cash flows, for example, deferred expenses, intangible assets, or income taxes.
Term Loan Two Thousand and Twenty Three Warrants [Member]
Term Loan Two Thousand and Twenty Three Warrants [Member]
2023 Warrants
Accounting Policies [Line Items]
Accounting Policies [Line Items]
Accounting policies.
Entity Address, Address Line One
Entity Address, Address Line One
2015 Plan
Two Thousand Fifteen Equity Compensation Plan [Member]
Represents information pertaining to the 2015 Equity Compensation Plan.
AXS-05
Axs05 [Member]
Represents information pertaining to AXS-05.
AXS-05.
Supplemental disclosures of cash flow information:
Supplemental Cash Flow Information [Abstract]
Rule 10b5-1 Trading Plan Two [Member]
Mark Coleman Two [Member]
Mark Coleman two.
Tranche Three Sub Tranche Two
Tranche Three Sub Tranche Two [Member]
Tranche three sub tranche two.
Contingent Consideration Type [Domain]
Royalty [Member]
Royalty Revenue
December 2019 Sales Agreement
December Two Thousand Nineteen Sales Agreement [Member]
December two thousand nineteen sales agreement.
Income tax benefit (expense)
Income tax benefit (expense)
Income Tax Expense (Benefit), Total
Income Tax Expense (Benefit)
Income tax expense
Provision for income taxes
Proceeds from draw down of debt
Proceeds from Long-Term Lines of Credit
Title
Trd Arr Ind Title
Trd Arr Ind Title.
Income Tax Disclosure [Text Block]
Income Taxes
Preferred Stock, Shares Issued, Total
Preferred stock, shares issued
Preferred Stock, Shares Issued
Payments to Acquire Property, Plant, and Equipment, Total
Purchases of equipment
Payments to Acquire Property, Plant, and Equipment
Income Tax Disclosure [Abstract]
Jazz Pharmaceuticals Plc
Jazz Pharmaceuticals Plc [Member]
Jazz pharmaceuticals Plc.
Royalty agreements disclosure text block
Royalty Agreements Disclosure [Text Block]
Royalty Agreements
Line Of Credit Facility [Table]
Line of Credit Facility [Table]
Disaggregation of Revenue [Abstract]
Revenue Recognition
Shares issued
Stock Issued During Period, Shares, New Issues
upfront payment received
upfront payment received
Non-refundable upfront payment received
Add: accreted liability of final payment fee
Debt Instrument Accreted Liability Of Final Payment Fee
Amount of accreted liability of final payment fee.
Rule 10b5-1 Trading Plan One [Member]
Mark Coleman One [Member]
Mark Coleman one.
Fair value share price
Share Price Fair Value
Fair value price of a single share of a number of saleable stocks of a company
Number of Reporting Units
Number of reporting units
Costs and Expenses
Total operating expenses
Fair Value Hierarchy and NAV [Axis]
Share-Based Payment Arrangement [Policy Text Block]
Stock-Based Compensation
Accrued Liabilities and Other Liabilities [Abstract]
Schedule Of Research And Development Arrangement Contract To Perform For Others [Table]
Schedule of Research and Development Arrangement, Contract to Perform for Others [Table]
Equity [Abstract]
Segment and Geographic Information
Segment Reporting, Disclosure of Entity's Reportable Segments [Abstract]
Weighted average exercise price, Forfeited
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Proceeds from issuance of common stock, net
Stock Issued During Period Value New Issues Net
Net equity impact of the value of new stock issued during the period. Includes shares issued in an initial public offering or a secondary public offering.
Loss from operations
Operating Income (Loss)
Loss from operations
Base interest rate
Debt Instrument, Interest Rate, Stated Percentage
Issuance of common stock upon vesting of RSUs
Stock Vested During Period Value Restricted Common Stock Award
Stock vested during period value restricted common stock award.
Share-based Compensation Arrangement by Share-based Payment Award, Options, Nonvested, Number of Shares, Ending Balance
Share-based Compensation Arrangement by Share-based Payment Award, Options, Nonvested, Number of Shares, Beginning Balance
Non-vested options outstanding
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Nonvested, Number of Shares
Related Party
Related Party [Domain]
Additional Paid in Capital, Common Stock, Ending Balance
Additional Paid in Capital, Common Stock, Beginning Balance
Additional paid-in capital
Additional Paid in Capital, Common Stock
Tranche Two Sub Tranche Two [Member]
Tranche two sub tranche two.
Tranche Two Sub Tranche Two
Scenario
Scenario [Axis]
Concentration Risk Benchmark [Domain]
Entity Filer Category
Entity Filer Category
Termination Date
Trd Arr Termination Date
Trd Arr Termination Date.
Fair Value by Liability Class [Domain]
Entity Current Reporting Status
Entity Current Reporting Status
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Current Assets, Other
Other current assets
Inventories, net
Inventory, Net
Inventories, net
Non-current inventory and other assets
Inventory, Noncurrent
Inventory, Noncurrent, Total
Prime Rate
Prime Rate [Member]
Inventory Disclosure [Text Block]
Inventory
Business combination consideration fair value of contingent consideration.
Business Combination Consideration Fair Value of Contingent Consideration
Fair value of contingent consideration
Stockholders' Equity
Stockholders' Equity Note Disclosure [Text Block]
Business Combinations [Abstract]
Business Combination
Finite-Lived Intangible Assets, Net, Beginning Balance
Finite-Lived Intangible Assets, Net, Ending Balance
Finite-Lived Intangible Assets, Net
Total
Total stockholders’ equity
Beginning balance
Ending balance
Stockholders' Equity Attributable to Parent
Investment Income, Net, Total
Investment Income, Net
Interest expense, net
Valuation, Income Approach [Member]
Probability weighted income approach
Commitments and Contingencies, Policy [Policy Text Block]
Contingent Consideration
2024
Long-Term Debt, Maturity, Year Two
45-day Period after Closing of Fourth Amendment to Loan and Security Agreement
Forty Five Day Period After Closing Of Fourth Amendment To Loan And Security Agreement [Member]
Forty five day period after closing of fourth amendment to loan and security agreement.
Percentage of final payment fee
Debt Instrument Final Payment Fee Threshold Percentage Of Debt Outstanding
The final payment fee to be paid under the debt arrangement as a percentage of aggregate amount of all term loan advances minus the aggregate amount of repayments made.
Entity Tax Identification Number
Entity Tax Identification Number
Income Statement Location
Income Statement Location [Axis]
Number of shares, Forfeited
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period
Common stock, $0.0001 par value per share (150,000,000 shares authorized, 46,726,794 and 43,498,617 shares issued and outstanding at June 30, 2023 and December 31, 2022, respectively)
Common Stock, Value, Issued, Ending Balance
Common Stock, Value, Issued, Beginning Balance
Common Stock, Value, Issued, Total
Value of common stock
Common Stock, Value, Issued
Fair Value, Assets and Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Abstract]
Retained Earnings (Accumulated Deficit), Ending Balance
Retained Earnings (Accumulated Deficit), Beginning Balance
Retained Earnings (Accumulated Deficit), Total
Accumulated deficit
Accumulated deficit
Retained Earnings (Accumulated Deficit)
Minimum product revenue percent
Long Term Debt Additional Drawn Minimum Revenue Percent
The minimum percentage of revenue should be achieved under the debt instrument.
Inventory reserves
Inventory Valuation Reserves
Equity Components
Equity Components [Axis]
Debt instrument prepayment occurring on or after february one two thousand twenty five but prior to february one two thousand twenty six.
Debt Instrument Prepayment Occurring On or After February One Two Thousand Twenty Five But Prior to February One Two Thousand Twenty Six [Member]
Prepayment Occurs On or After February 1, 2025 but Prior to February 1, 2026
Finite lived intangible assets amortization expense after year four.
Finite Lived Intangible Assets Amortization Expense After Year Four
Thereafter
Cash Equivalents
Cash and Cash Equivalents, Policy [Policy Text Block]
Reserves for Variable Consideration.
Reserves for Variable Consideration
Less: Reserves for Variable Consideration
Entity Emerging Growth Company
Entity Emerging Growth Company
Summary of Balance Sheet Classification of Inventory
Schedule of Inventory, Noncurrent [Table Text Block]
Schedule of Business Acquisitions, by Acquisition [Table]
Operating Expenses [Abstract]
Operating expenses:
Revision of Prior Period, Adjustment [Member]
Restatement Adjustment
Schedule of Accounts, Notes, Loans and Financing Receivable [Table Text Block]
Schedule of Accounts Receivable, Net
Issuance of common stock upon vesting of RSUs (in shares)
Stock Vested During Period Shares Restricted Common Stock Award
Stock vested during period shares restricted common stock award.
Common stock, voting right per share
Equity Instrument Voting Rights Per Share
Represents the number of votes per share each holder of shares is entitled to.
Revenue [Policy Text Block]
Revenue Recognition
Schedule of Deferred Compensation Arrangement with Individual, Excluding Share-Based Payments and Postretirement Benefits, by Title of Individual and by Type of Deferred Compensation [Table]
Cost of Revenue, Total
Cost of Revenue
Cost of product sales
Cost of product sales
Lessee, Operating Lease, Liability, to be Paid [Abstract]
Investment, Name
Investment, Name [Axis]
Accrued expenses and other current liabilities
Increase (Decrease) in Other Accounts Payable and Accrued Liabilities
Weighted average contractual term
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Additional Disclosures [Abstract]
Minimum percentage of cash to be maintained as a security
Long Term Debt Additional Drawn Covenant Minimum Cash To Be Maintained As Security Percent
The minimum percentage of cash to be maintained under debt instruments.
Document Transition Report
Document Transition Report
2025
Long-Term Debt, Maturity, Year Three
Weighted average grant date fair value, Granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value
Non-Rule 10b5-1 Arrangement Terminated
Non-Rule 10b5-1 Arrangement Terminated
Tranche one.
Tranche One [Member]
Tranche One
SVB Securities
SVB Securities Limited Liability Company [Member]
SVB Securities Limited Liability Company.
Commitments and Contingencies
Commitments and Contingencies Disclosure [Text Block]
Weighted average exercise price, Exercised
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Number of shares
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward]
Accounts Receivable, after Allowance for Credit Loss, Current
Accounts receivables, net
Accounts Receivables, net
Accounts Receivable, net
Entity Common Stock, Shares Outstanding
Entity Common Stock, Shares Outstanding
Research And Development Arrangement Contract To Perform For Others [Line Items]
Research and Development Arrangement, Contract to Perform for Others [Line Items]
Term loan advances.
Term Loan Advances [Member]
Term Loan Advances
Amortization of debt issuance costs
Amortization of Debt Issuance Costs
Amortization of final payment fee
Total
Accrued expenses and other current liabilities
Accounts Payable and Other Accrued Liabilities, Current
Less: current portion of long-term debt
Long Term Debt Current Net Of Noncurrent Debt Discount
Amount, after noncurrent portion of unamortized (discount) premium and debt issuance costs, of long-term debt. Includes, but not limited to, notes payable, bonds payable, debentures, mortgage loans and commercial paper. Excludes capital lease obligations.
Revision of Prior Period [Domain]
Operating lease, expiration month and year
Operating Lease Expiration Month And Year
Operating lease, expiration month and year.
Net loss
Net loss
Net Income (Loss) Attributable to Parent
Thereafter
Lessee Operating Lease Liability Payments Due After Year Four
Lessee operating lease liability payments due after year four.
Operating lease liability, current portion
Operating Lease, Liability, Current
Royalty agreements.
Royalty Agreements [Abstract]
Upfront cash payment
Initial Cash Payment Per Collaboration Agreement
Initial Cash Payment Per Collaboration Agreement.
Additional Paid-in Capital
Additional Paid-in Capital [Member]
Collaborative Arrangement and Arrangement Other than Collaborative
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
License agreement royalty, maximum reduction percent as a result of required third party payments
License Agreement Royalty Due Maximum Reduction Percentage As Result Of Required Payments To Third Parties
Represents the maximum reduction percentage of the royalty due as a result of required payments to third parties.
Schedule of Purchase Consideration
Schedule of business acquisition of preliminary purchase consideration.
Schedule of Business Acquisition of Preliminary Purchase Consideration [Table Text Block]
Payments of tax withholdings on stock award
Payment, Tax Withholding, Share-Based Payment Arrangement
Unobservable input weighted average rate.
Unobservable Input Weighted Average Rate
Unobservable input weighted average rate
Schedule of Principal Payments
Schedule of Maturities of Long-Term Debt [Table Text Block]
Fair Value Measurement Inputs and Valuation Techniques [Table Text Block]
Schedule of fair value measurements of contingent consideration recurring include significant unobservable inputs
Entity Registrant Name
Entity Registrant Name
Advertising Expense
Advertising costs
Liabilities, Fair Value Disclosure
Total
Cash and Cash Equivalents, at Carrying Value, Ending Balance
Cash and Cash Equivalents, at Carrying Value, Beginning Balance
Cash and Cash Equivalents, at Carrying Value, Total
Cash and cash equivalents
Cash and Cash Equivalents, at Carrying Value
Net Loss per Common Share
Earnings Per Share [Text Block]
Lessee, Lease, Description [Table]
Revenues, Total
Revenues
Sales
Share-based Payment Arrangement, Noncash Expense, Total
Stock-based compensation expense
Share-Based Payment Arrangement, Noncash Expense
Property, Plant and Equipment, Net, Ending Balance
Property, Plant and Equipment, Net, Beginning Balance
Property, Plant and Equipment, Net, Total
Equipment, net
Property, Plant and Equipment, Net
Weighted average contractual term, Vested and expected to vest
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term
Award Type
Award Type [Domain]
Statement [Line Items]
Statement [Line Items]
Exercised (in dollars per share)
Warrants Exercised In Period Weighted Average Exercise Price
Weighted average price at which warrants were exercised.
Weighted average exercise price, Vested and expected to vest
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price
Title of 12(b) Security
Title of 12(b) Security
Finite-Lived Intangible Assets, Gross, Total
Finite-Lived Intangible Assets, Gross
Gross Carrying Amount
Balance at December 31, 2022
Term of warrants (in years)
Class Of Warrant Or Right Term
Period during which warrants are active, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.
Increase (Decrease) in Accounts Payable, Total
Accounts payable
Increase (Decrease) in Accounts Payable
Antecip
Affiliated Entity [Member]
Antecip.
Common Stock
Common Stock [Member]
Cost of Goods and Service, Excluding Depreciation, Depletion, and Amortization
Cost of product sales (excluding amortization and depreciation)
Cost of revenue (excluding amortization and depreciation)
Tranche one sub tranche four.
Tranche One Sub Tranche Four [Member]
Tranche One Sub Tranche Four
Cash flows from operating activities
Net Cash Provided by (Used in) Operating Activities [Abstract]
Equity Component
Equity Component [Domain]
Fair Value Measurement, Policy [Policy Text Block]
Fair Value Measurements
Revenue from Contract with Customer, Excluding Assessed Tax
Revenue
Product sales
Revenue from Contract with Customer, Excluding Assessed Tax, Total
Loss before income taxes
Loss before income taxes
Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest
Entity Address, State or Province
Entity Address, State or Province
2027
Lessee, Operating Lease, Liability, to be Paid, Year Four
Geographical [Axis]
Tranche one sub tranche two.
Tranche One Sub Tranche Two [Member]
Tranche One Sub Tranche Two
Net (decrease) increase in cash
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect
Document Type
Document Type
Interest paid
Interest Paid, Excluding Capitalized Interest, Operating Activities
Business Acquisition, Pro Forma Information [Table Text Block]
Schedule of Unaudited Pro Forma Summary Presents Consolidated Information
Goodwill Disclosure [Text Block]
Goodwill
Shares tendered for withholding taxes
Adjustments To Additional Paid In Capital Shares Tendered For Withholding Taxes
Adjustments to Additional paid-in capital Shares tendered for withholding taxes.
Receivables [Abstract]
Accounts Receivable, net
Entity Shell Company
Entity Shell Company
Number of warrants outstanding beginning balance
Number of warrants outstanding ending balance
Class of Warrant or Right, Outstanding
Increase (Decrease) in Inventories, Total
Increase (Decrease) in Inventories
Inventories, net
Expense
Stock-based compensation expense
Share-Based Payment Arrangement, Expense
Business combination, step-up inventory fair value.
Business Combination, Step-Up Inventory Fair Value
Inventory step-up fair value
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Percentage of facility fee to be paid.
Percentage Of Facility Fee To Be Paid
Percentage of facility fee to be paid
Fair Value, Recurring and Nonrecurring [Table]
Loss Contingencies [Line Items]
Loss Contingencies [Line Items]
Accrued selling, general and administrative current.
Accrued Selling, General and Administrative Current
Accrued selling, general and administrative
Security Exchange Name
Security Exchange Name
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Summary of Significant Accounting Policies
Significant Accounting Policies [Text Block]
Revenue discount rate increases or decreases by one percentage.
Revenue Discount Rate Increases or Decreases by One Percentage [Member]
Revenue Discount Rate Increases or Decreases by Approximately 1%
Net cash used in operating activities
Net Cash Provided by (Used in) Operating Activities
December 2019 and March 2022 Sales Agreement
December Two Thousand Nineteen and March Two Thousand Twenty Two Sales Agreement [Member]
December two thousand nineteen and march two thousand twenty two sales agreement.
Expected vesting period for non-vested share-based compensation
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Weighted average contractual term, Outstanding
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Fair Value, by Balance Sheet Grouping [Table]
Payments to Acquire Businesses, Gross
Cash paid for business combination
Cash at settlement
Commitments and Contingencies Disclosure [Abstract]
Total operating lease expense
Operating Lease, Cost
Accrued Interest
Interest Payable, Current
Restricted Stock Units
Restricted Stock Units (RSUs) [Member]
Schedule of Future Minimum Lease Payments of Operating Leases
Lessee, Operating Lease, Liability, Maturity [Table Text Block]
Business Acquisition, Pro Forma Revenue
Net revenues
Warrants
Warrant [Member]
Summary of Stock Option Activity
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
Recent Accounting Pronouncements
New Accounting Pronouncements, Policy [Policy Text Block]
Common Stock, Shares, Outstanding, Ending Balance
Common Stock, Shares, Outstanding, Beginning Balance
Common stock, shares outstanding
Common Stock, Shares, Outstanding
Business Acquisition [Line Items]
Cost of Goods and Service [Policy Text Block]
Cost of Revenue
Inventory, Work in Process, Gross
Work in process
Accrued Royalties, Current
Accrued royalties
Fair Value, Inputs, Level 2 [Member]
Level 2
Term Loan2020 [Member]
Represents about term loan two thousand twenty.
Term Loan 2020
Measurement Input, Revenue Multiple [Member]
Revenue Discount rate
Cash flows from investing activities
Net Cash Provided by (Used in) Investing Activities [Abstract]
Schedule of Finite-Lived Intangible Assets, Future Amortization Expense [Table Text Block]
Schedule of Finite Lived Intangible Assets Future Amortization Expense
Common Stock, Shares, Issued, Total
Number of common shares
Common stock, shares issued
Balance (in shares)
Balance (in shares)
Common Stock, Shares, Issued
Variable Rate
Variable Rate [Domain]
Minimum
Minimum
Number of exclusive license agreements
Number Of License Agreements
Represents the number of license agreements the Company has entered into.
Leases
Lessee, Leases [Policy Text Block]
Weighted average exercise price, Exercisable
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Debt Instrument
Debt Instrument [Axis]
Stockholders’ equity:
Stockholders' Equity Attributable to Parent [Abstract]
Counterparty Name
Counterparty Name [Axis]
Entity Address, Address Line Two
Entity Address, Address Line Two
Foreign Currency Translation
Foreign Currency Transactions and Translations Policy [Policy Text Block]
Revenues [Abstract]
Weighted average grant date fair value, Forfeited
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value
Product [Member]
Product Sales
Discount rate increases or decreases by one percentage.
Discount Rate Increases or Decreases by One Percentage [Member]
Discount Rate Increases or Decreases by Approximately 1%
Amortization of Intangible Assets
Amortization of intangible asset
Intangible asset amortization
License agreement royalty as a percent of net sales
License Agreement Royalty Due Percentage Of Net Sales
Represents the percentage of net sales of products containing the licensed products, due to licensor as a royalty.
License agreement royalty as a percent of net sale
Award Type
Award Type [Axis]
Subsequent Event [Member]
Subsequent Event
Business Combination, Consideration Transferred
Cash and contingent consideration
Total
Loss Contingencies [Table]
Loss Contingencies [Table]
Research and Development Expense, Total
Research and development expense recognized
Research and development
Research and Development Expense
Total lease payments
Lessee, Operating Lease, Liability, to be Paid
Issuance of common stock
Issuance of common stock upon financing (in shares)
Stock Issued During Period Shares Financing
Number of shares of stock issued during the period pursuant to a financing arrangement.
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Payments
Expected cash dividend
Payment of contingent consideration
Payment Of Contingent Consideration
Tranche One Sub Tranche One [Member]
Tranche One Sub Tranche One [Member]
Tranche One Sub Tranche One
Entity Central Index Key
Entity Central Index Key
Warrant liability
Warrant Liability [Member]
Warrant liability.
Advertising Cost [Policy Text Block]
Advertising Costs
Eligible to receive sales-based and other milestones
Eligible to receive sales-based and other milestones
Eligible to receive sales-based and other milestones
Business Combination, Contingent Consideration, Liability, Noncurrent
Contingent consideration, non-current
Contingent consideration liability, non-current
AXS-04
Axs04 [Member]
Represents information pertaining to AXS-04.
AXS-05 and AXS-07
Axs05 And Axs07 [Member]
Represents the information pertaining to AXS-05 and AXS-07.
Customer [Axis]
Accounting Policies [Abstract]
Tranche one sub tranche five.
Tranche One Sub Tranche Five [Member]
Tranche One Sub Tranche Five
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Abstract]
Measurement Frequency [Axis]
Interest expense
Interest Expense, Debt, Excluding Amortization
Shares available for future grant
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant
Trading days
Class Of Warrants Or Rights Weighted Average Price Trading Days
Threshold period of specified consecutive trading days within which the volume weighted average price of company's common stock.
Aggregate intrinsic value, Vested and expected to vest
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value
Sunosi
Sunosi [Member]
Sunosi.
Business Combination, Contingent Consideration, Liability, Current
Contingent consideration, current
Accrued contingent consideration, current
Subsequent Event [Table]
Measurement Input Type [Domain]
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Weighted average exercise price, Outstanding, beginning balance
Weighted average exercise price, Outstanding, ending balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Research and Development
Research and Development Expense [Member]
Operating lease right-of-use asset obtained in exchange for operating lease liability
Right-of-Use Asset Obtained in Exchange for Operating Lease Liability
22 Cortlandt Street Lease
Leased Office Space [Member]
Leased office space.
Accumulated Deficit
Retained Earnings [Member]
Customer [Domain]
Measurement Input Type [Axis]
Effective Income Tax Rate Reconciliation, Percent, Total
Effective tax rate
Effective Income Tax Rate Reconciliation, Percent
Effective tax rate
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Research and Development Arrangement, Contract to Perform for Others, Type
Research and Development Arrangement, Contract to Perform for Others, Type [Axis]
Long-Term Debt, Maturity, after Year Five
Thereafter
Entity Interactive Data Current
Entity Interactive Data Current
Number of shares, Vested and expected to vest
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number
Supplemental non-cash investing activities:
Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract]
Minimum percentage of cash to be maintained as a security following market capitalization condition
Long Term Debt Additional Drawn Covenant Minimum Cash To Be Maintained As Security With Market Capitalization Covenant Percent
The minimum percentage of cash to be maintained as security following the market capitalization conditions under the debt instruments.
2024
Lessee, Operating Lease, Liability, to be Paid, Year One
License [Member]
License Fee
License Revenue
Proceeds from Issuance of Warrants
Issuance of warrants
Local Phone Number
Local Phone Number
Schedule of Allocation of Fair Value
Schedule of Recognized Identified Assets Acquired and Liabilities Assumed [Table Text Block]
Computation of Basic and Diluted Net Loss per Common Share
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
Vesting period
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period
Debt Disclosure [Abstract]
Number of approved products
Number of approved products.
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Number of shares, Exercisable
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number
Warrants and Rights Note Disclosure [Abstract]
Lender Name [Axis]
Number of shares, Granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Sublease agreement term
Sublease Agreement Term
Sublease agreement term.
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Table Text Block]
Schedule of fair value of the contingent consideration remeasured
Fair Value Measurement Inputs and Valuation Techniques [Abstract]
Milestone dates [Member].
Milestone Dates [Member]
Milestone dates
Income Statement Location
Income Statement Location [Domain]
Outstanding principle and advances under the loans agreement exceeds 55 million
Outstanding Advances Under Loan Agreement Equals Or Exceeds Fifty Five Million [Member]
Represents the information if the outstanding principle and advances under loan agreement exceeds fifty five million.
2023
Long-Term Debt, Maturity, Year One
Tranche two sub tranches to one tranche.
Tranche Two Sub Tranches To One Tranche [Member]
Tranche Two Sub Tranches To One Tranche
Selling, General and Administrative Expenses [Member]
Selling, General and Administrative Expenses
Property, Plant and Equipment [Abstract]
Equipment, net
Number of shares, Outstanding, beginning balance
Number of shares, Outstanding, ending balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number
Long-term Debt, Total
Outstanding amount
Long-Term Debt
Long term
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Long Term debt additional drawn covenant minimum cash.
Long Term Debt Additional Drawn Covenant Minimum Cash
Increase in minimum cash requirement amount
Inventory Disclosure [Abstract]
Contingent Consideration by Type [Axis]
Underwritten Public Offering
Underwritten Public Offering [Member]
An underwritten sale of stock.
Customer Concentration Risk [Member]
'Customer Concentration Risk
Number of shares, Outstanding, beginning balance
Number of shares, Outstanding, ending balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Share price
Share Price
Share Price
Upfront payment
Upfront Payment
Upfront payment.
Fair Value, Liabilities Measured on Recurring Basis [Table Text Block]
Schedule of fair value of financial instruments measured on a recurring basis
Debt Instrument, Name
Debt Instrument, Name [Domain]
Document Fiscal Year Focus
Document Fiscal Year Focus
Net Book Value at June 30, 2023
Intangible Assets, Net (Excluding Goodwill)
Intangible asset, net
Balance at December 31, 2022
Net Book Value at March 31, 2023
Payments of Debt Issuance Costs
Payment of debt issuance costs
Measurement period adjustment
Goodwill, Period Increase (Decrease)
Goodwill, Period Increase (Decrease), Total
2025
Lessee, Operating Lease, Liability, to be Paid, Year Two
Earnings Per Share, Basic, Total
Earnings Per Share, Basic
Net loss per common share, basic
Weighted average exercise price
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract]
Assets
Assets [Abstract]
Schedule of Outstanding Debt and Unamortized Debt Discount Balances
Schedule of Long-Term Debt Instruments [Table Text Block]
Prepaid and other current assets
Prepaid Expense and Other Assets, Current
Fair value of contingent consideration in a business combination
Fair Value Of Contingent Consideration In A Business Combination
Fair value of contingent consideration in a business combination.
Long-Lived Tangible Asset [Axis]
Accrued Royalties
Accrued royalty payments
Change in operating lease liability
Change In Operating Lease Liability
Change in operating lease liability.
Concentration Risk Benchmark [Axis]
Number of shares
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward]
Liabilities and stockholders’ equity
Liabilities and Equity [Abstract]
Property, Plant and Equipment, Policy [Policy Text Block]
Equipment, net
Aggregate Available
Trd Arr Securities Agg Avail Amt
Trd Arr Securities Agg Avail Amt.
Antidilutive Securities, Name
Antidilutive Securities, Name [Domain]
Initial estimate (Level 3)
Fair value measurement with unobservable inputs reconciliations recurring basis liability initial estimate.
Fair Value Measurement With Unobservable Inputs Reconciliations Recurring Basis Liability Initial Estimate
Valuation Approach and Technique [Axis]
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total
Net loss
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest
Significant Risks And Uncertainties
Significant Risks And Uncertainties Policy Policy [Text Block]
Disclosure of accounting policy for significant risks and uncertainties.
Current assets:
Assets, Current [Abstract]
Finite-Lived Intangible Asset, Expected Amortization, Year Four
2027
Finite-Lived Intangible Asset, Expected Amortization, Year Two
2025
Exercise price of warrants (in dollars per share)
Weighted average exercise price, Beginning balance
Weighted average exercise price, Ending balance
Class of Warrant or Right, Exercise Price of Warrants or Rights
Customer One.
Customer One [Member]
Customer One
Schedule of Goodwill [Table Text Block]
Schedule of Goodwill
Fair Value Hierarchy and NAV [Domain]
Measurement Frequency [Domain]
Warrants Issued During Period Debt Financing
Warrants issued during period debt financing.
Issuance of warrants upon debt financing
Changes in operating assets and liabilities:
Increase (Decrease) in Operating Capital [Abstract]
Number of warrants issued
Warrants Issued In Period
Number of warrants (or share units) issued during the current period.
Accrued Sales Commission, Current
Accrued sales discounts, rebates and allowances
Tranche three sub tranches to one tranche.
Tranche Three Sub Tranches To One Tranche [Member]
Tranche Three Sub Tranches to One Tranche
Cover [Abstract]
Non-Rule 10b5-1 Arrangement Adopted
Non-Rule 10b5-1 Arrangement Adopted
Concentration Risk, Percentage
Concentration risk, percentage
Product and Service
Product and Service [Domain]
Pharmanovia.
Pharmanovia [Member]
Pharmanovia
Number of shares, Vested
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period
Inventory, Finished Goods, Gross
Finished goods
Goodwill, Impairment Loss
Goodwill impairment
Prior trading days
Consecutive Trading Days
Represents the consecutive number of trading days to determine the weighted average price per share of ordinary shares.
Cost of Revenue [Abstract]
Cost of Product Sales
Current liabilities:
Liabilities, Current [Abstract]
Maximum
Maximum
License agreement term, from first commercial sale
License Agreement Term
Period of time, after the first commercial sale of the applicable product, the license agreement is valid, in PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.
Schedule of interest and amortization expense for final payment fee and debt discount.
Schedule of Interest and Amortization Expense for Final Payment Fee and Debt Discount [Table Text Block]
Schedule of Interest and Amortization Expense for Final Payment Fee and Debt Discount
Schedule of Stock-Based Compensation Expense Recognized
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
Customer Three.
Customer Three [Member]
Customer Three
Net cash used in investing activities
Net Cash Provided by (Used in) Investing Activities
Tranche one sub tranche three.
Tranche One Sub Tranche Three [Member]
Tranche One Sub Tranche Three
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table]
Number of not yet approved product candidates
Number of Not Yet Approved Product Candidates
Number of not yet approved product candidates.
Number of shares, Exercised
Issuance of common stock upon exercise of options (in shares)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period
Schedule of Inventory, Current [Table Text Block]
Schedule of Inventory
Fair Value, Inputs, Level 3 [Member]
Level 3
Use of Estimates
Use of Estimates, Policy [Policy Text Block]
Interest rate basis
Debt Instrument, Basis Spread on Variable Rate
Hercules Capital Inc
Hercules Capital Inc [Member]
Hercules Capital Inc.
Cash Equivalents, at Carrying Value, Total
Cash Equivalents
Cash Equivalents, at Carrying Value
Cash
Insider Trading Arr Abstract
Insider Trading Arr Abstract
Accounts Receivable [Member]
Accounts Receivable
2022
Long-Term Debt, Maturity, Remainder of Fiscal Year
Issuance of common stock upon exercise of options
Stock Issued During Period, Value, Stock Options Exercised
Segment and Geographic Information
Segment Reporting, Policy [Policy Text Block]
Aggregate intrinsic value, Exercisable
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Aggregate Intrinsic Value
Estimated useful life
Property, Plant and Equipment, Useful Life
Total principal payments outstanding
Total Outstanding Debt
Long-Term Debt, Gross
Finite-Lived Intangible Asset, Expected Amortization, Year Three
2026
Common stock, shares authorized
Common Stock, Shares Authorized
March 2022 Sales Agreement
March Two Thousand Twenty Two Sales Agreement [Member]
March Two Thousand Twenty Two Sales Agreement [Member]
Percentage of prepayment penalty
Debt Instrument Prepayment Penalty Percentage
Represents the prepayment penalty percentage on principal amount of debt.
Trading Symbol
Trading Symbol
Minimum cash to be maintain as a first priority security interest
Long Term Debt Additional Drawn Covenant Minimum Cash As Security Interest
The minimum amount of cash should be maintained as first priority security interest under the terms of debt instrument.
December 2019, August 222 and March 2022 Sales Agreement
December Two Thousand Nineteen March Two Thousand Twenty Two and August Two Thousand Twenty Two Sales Agreement [Member]
December two thousand nineteen, march two thousand twenty two and august two thousand twenty two sales agreement.
Selling, General and Administrative Expense, Total
Selling, General and Administrative Expense
Selling, general and administrative
Non-cash lease expense
Non Cash Lease Expense
Non-cash lease expense.
Title of Individual [Domain]
Subsequent Event Type [Axis]
Term Loan
Term Loan [Member]
Term loan.
Tranche Two Sub Tranche Three [Member]
Tranche two sub tranche three.
Tranche Two Sub Tranche Three
Accounts Payable, Current, Total
Accounts payable
Accounts Payable, Current
Payments
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Liability, Settlements
Plan Name
Plan Name [Axis]
Title of Individual [Axis]
Concentration Risk Type [Domain]
Long-Lived Tangible Asset [Domain]
Common stock, par value
Common Stock, Par or Stated Value Per Share
Schedule of RSU Activity
Share-Based Payment Arrangement, Restricted Stock and Restricted Stock Unit, Activity [Table Text Block]
Number of shares, Granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period
June 2023 Public Offering
June Two Thousand Twenty Three Public Offering [Member]
June two thousand twenty three public offering.
Weighted average exercise price, Granted
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Business combination recognized identifiable assets acquired and liabilities assumed current assets developed technology.
Business Combination Recognized Identifiable Assets Acquired and Liabilities Assumed Current Assets Developed Technology
Developed technology
Loan and Security Agreement
Long-Term Debt [Text Block]
Long-Term Debt, Type [Domain]
Antidilutive securities
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount