Lessee, operating lease, description Lessee, Operating Lease, Description Vesting period Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period Prepayment Occurs Prior to First Anniversary of First Amendment Closing Date Debt Instrument Prepayment Occurring Prior To First Anniversary Of First Amendment Closing Date [Member] Debt instrument prepayment occurring prior to first anniversary of first amendment closing date. Segment and Geographic Information Segment Reporting, Policy [Policy Text Block] Weighted average contractual term Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Outstanding, Weighted Average Remaining Contractual Terms Forecast Forecast [Member] Fair value of common stock Common Stock Fair Value Fair value of issued nonredeemable common stock (or common stock redeemable solely at the option of the issuer). This item includes treasury stock repurchased by the entity. Note: elements for number of nonredeemable common shares, par value and other disclosure concepts are in another section within stockholders' equity. Operating expenses: Operating Expenses [Abstract] Loss from operations Operating Income (Loss) Operating lease liability Increase (Decrease) in Operating Lease Liability Schedule of Outstanding Debt and Unamortized Debt Discount Balances Schedule of Long-term Debt Instruments [Table Text Block] Entity Emerging Growth Company Entity Emerging Growth Company Weighted average grant date fair value, Forfeited Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value Shares available for future grant Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant Payments to Acquire Property, Plant, and Equipment, Total Purchases of equipment Payments to Acquire Property, Plant, and Equipment Common stock, $0.0001 par value per share (150,000,000 shares authorized, 38,883,445 and 37,816,794 shares issued and outstanding at March 31, 2022 and December 31, 2021, respectively) Common Stock, Value, Issued, Ending Balance Common Stock, Value, Issued, Beginning Balance Common Stock, Value, Issued, Total Value of common stock Common Stock, Value, Issued Schedule of RSU Activity Share-based Payment Arrangement, Restricted Stock and Restricted Stock Unit, Activity [Table Text Block] Entity Address, State or Province Entity Address, State or Province Total liabilities Liabilities Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table] Share-based Payment Arrangement, Expensed and Capitalized, Amount [Table] Debt Issuance Costs Debt, Policy [Policy Text Block] Period to achieve second milestone Threshold Days To Achieve Second Milestone Number of days to achieve second milestone following such date. Common stock sales agreement, authorized amount Common Stock Sales Agreement Authorized Amount The authorized amount under a common stock sales agreement. Payments of tax withholdings on stock award Payment, Tax Withholding, Share-based Payment Arrangement License Agreement License Agreement Terms [Member] Debt instrument maturity, month and year Debt Instruments Maturity Month And Year Debt instruments maturity, month and year. Term loan 2020 tranche one Term Loan2020 Tranche One [Member] Represents about term loan tranche one. Weighted average common shares outstanding, basic and diluted Weighted Average Number of Shares Outstanding, Basic and Diluted Number of shares Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding [Roll Forward] Schedule of Warrant Activity Schedule of Stockholders' Equity Note, Warrants or Rights [Table Text Block] General and Administrative General and Administrative Expense [Member] Remaining credit facility to be drawn Line of Credit Facility, Remaining Borrowing Capacity Weighted average contractual term, Exercisable Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term Number of late-stage candidates in Company's product candidate portfolio Number Of Late Stage Product Candidates Represents the number of late-stage candidates included in the Company's product candidate portfolio. Debt Instrument Prepayment Occurs On Or After Second Anniversary And Prior To Third Anniversary Of First Amendment Closing Date [Member] Debt instrument prepayment occurs on or after second anniversary and prior to third anniversary of first amendment closing date. Prepayment Occurs on or After Second Anniversary and Prior to Third Anniversary of First Amendment Closing Date Summary of Significant Accounting Policies Significant Accounting Policies [Text Block] City Area Code City Area Code Term loan 2020 tranche two Term Loan2020 Tranche Two [Member] Represents about term loan tranche two. Cash pay interest rate Debt Instrument Threshold Cash Pay Interest Rate Effective cash pay interest rate for the funds borrowed under the debt agreement considering interest compounding and original issue discount or premium. Weighted average grant date fair value Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value [Abstract] Tranche Two Sub-Tranche One Tranche Two Sub Tranche One [Member] Tranche two sub tranche one. Change in accounting principle, accounting standards update, adopted Change in Accounting Principle, Accounting Standards Update, Adopted [true false] Weighted average exercise price, Forfeited Share-based Compensation Arrangements by Share-based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price Unregistered common stock value Unregistered common stock value. Final payment fee Extinguishment Of Debt Fee Amount The final payment fee at extinguishment of debt. Schedule of Potentially Dilutive Securities Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Future milestone payments Collaboration Arrangement Future Potential Payments The amount of future payments payable under the collaboration arrangement. Minimum amount of market capital to be maintained Long Term Debt Additional Drawn Covenant Minimum Market Capitalization Amount The minimum amount of market capital to be maintained under debt instruments. Shares issued Stock Issued During Period, Shares, New Issues Aggregate intrinsic value Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest [Abstract] Interest rate basis Debt Instrument, Basis Spread on Variable Rate Scenario Scenario [Axis] Milestone payments or royalties Royalty Expense Cash at end of period Cash at beginning of period Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Total Related Party Related Party [Domain] Change in accounting principle, accounting standards update, immaterial effect Change in Accounting Principle, Accounting Standards Update, Immaterial Effect [true false] Income Statement [Abstract] Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table] Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Antecip Affiliated Entity [Member] Net cash used in investing activities Net Cash Provided by (Used in) Investing Activities Fair value Fair Value Of Warrants The fair value of outstanding warrants. Employee-related Liabilities, Current, Total Accrued compensation Employee-related Liabilities, Current General and Administrative Expense, Total General and administrative General and Administrative Expense Property, Plant and Equipment, Net, Ending Balance Property, Plant and Equipment, Net, Beginning Balance Property, Plant and Equipment, Net, Total Equipment, net Property, Plant and Equipment, Net Revenue milestones Revenue Milestones Revenue milestones. Common Stock, Shares, Issued, Total Number of common shares Common stock, shares issued Balance (in shares) Balance (in shares) Common Stock, Shares, Issued Period of unpaid invoices amount maintain as security Long Term Debt Additional Drawn Covenant Additional Security Unpaid Invoices Period The period of unpaid invoices after threshold period respective amount should be keep as a security under the debt instruments. Number of shares, Forfeited Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Forfeited in Period Prepayment Occurs Prior to First Anniversary of Closing Date Debt Instrument Prepayment Occurring Prior To First Anniversary Of Closing Date [Member] Represents the prepayment of debt occurring prior to first anniversary of closing date. Subject to FDA Approval of AXS-05 and AXS-07 Subject To FDA Approval Of AXS Zero Five And AXS Zero Seven [Member] Subject to FDA approval of AXS zero five and AXS zero seven. AXS-02 Axs02 [Member] Represents information pertaining to AXS-02. Right-of-use asset - operating lease Operating Lease, Right-of-Use Asset Security Exchange Name Security Exchange Name Statistical Measurement Statistical Measurement [Domain] Concentration of Credit Risk Risks and Uncertainties [Abstract] 2025 Long-Term Debt, Maturity, Year Three Accrued general and administrative Accrued General And Administrative Current Accrued general and administrative current. 2019-12 Accounting Standards Update 2019-12 [Member] Tranche Three Sub Tranche One Tranche Three Sub Tranche One [Member] Tranche three sub tranche one. Issued (in dollars per share) Warrants Issued In Period Weighted Average Exercise Price Weighted average price at which warrants were issued. Maximum loan amount Line of Credit Facility, Maximum Borrowing Capacity Debt Disclosure [Abstract] SVB Leerink Leerink Partners Limited Liability Company [Member] SVB Leerink limited liability company. Document Period End Date Document Period End Date Income Statement Location Income Statement Location [Axis] Line of Credit Facility, Lender [Domain] Warrants Warrant [Member] Loss Contingencies [Table] Loss Contingencies [Table] Common stock, shares authorized Common Stock, Shares Authorized Use of Estimates Use of Estimates, Policy [Policy Text Block] Operating lease liability, current portion Operating Lease, Liability, Current Related Party Related Party [Axis] Supplemental disclosures of cash flow information: Supplemental Cash Flow Information [Abstract] Antidilutive securities Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount 2024 Long-Term Debt, Maturity, Year Two Schedule of Long-term Debt Instruments [Table] Common stock sales agreement, commission percentage Common Stock Sales Agreement Commission Percentage The commission percentage paid under a common stock sales agreement. Interest paid Interest Paid, Excluding Capitalized Interest, Operating Activities Accrued Expenses and Other Current Liabilities Accounts Payable and Accrued Liabilities Disclosure [Text Block] License Agreements License Agreements Disclosure [Text Block] The entire disclosure for license agreements. Effective Income Tax Rate Reconciliation, Percent, Total Effective tax rate Effective Income Tax Rate Reconciliation, Percent Number of shares, Expired Share Based Compensation Arrangement By Share Based Payment Award Options Expired In Period Share based compensation arrangement by share based payment award options expired in period. Entity Address, Address Line Two Entity Address, Address Line Two Current Fiscal Year End Date Current Fiscal Year End Date Net (decrease) increase in cash Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect Total operating lease expense Operating Lease, Cost Number of financial institutions that hold the Company's cash Number Of Financial Institutions Holding Deposits Represents the number of financial institutions holding the Company's cash. Issuance of common stock upon financing Stock Issued During Period Value Financing Value of stock issued pursuant to a financing arrangement during the period. Lessee, operating lease, existence of option to extend [true false] Line Of Credit Facility [Line Items] Line of Credit Facility [Line Items] Pfizer Inc Pfizer Inc [Member] Information pertaining to Pfizer, Inc. Number of Asian markets Number of Asian Markets Number of Asian markets. Counterparty Name Counterparty Name [Axis] Assets Assets [Abstract] 2023 Lessee, Operating Lease, Liability, to be Paid, Year One Accounts Payable, Current, Total Accounts payable Accounts Payable, Current Debt Instrument, Name Debt Instrument, Name [Domain] Common stock, par value Common Stock, Par or Stated Value Per Share Investment, Name Investment, Name [Axis] Additional Paid in Capital, Common Stock, Ending Balance Additional Paid in Capital, Common Stock, Beginning Balance Additional paid-in capital Additional Paid in Capital, Common Stock Research and Development Costs Research and Development Expense, Policy [Policy Text Block] Document Type Document Type Accrued research and development Accrued Research And Development Current Carrying value as of the balance sheet date of obligations incurred through that date and payable for research and development. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). Common stock sales agreement, shares unsold amount Common Stock Sales Agreement Shares Unsold Amount Common stock sales agreement shares unsold amount. Income Taxes Effective Income Tax Rate Reconciliation, Percent [Abstract] Preferred stock, $0.0001 par value per share (10,000,000 shares authorized, none issued and outstanding at March 31, 2022 and December 31, 2021, respectively) Preferred Stock, Value, Issued, Beginning Balance Preferred Stock, Value, Issued, Total Preferred Stock, Value, Issued, Ending Balance Preferred Stock, Value, Issued Operating lease liability, long-term Operating Lease, Liability, Noncurrent Total Accrued expenses and other current liabilities Accounts Payable and Other Accrued Liabilities, Current Schedule of Accrued Expenses Schedule of Accrued Liabilities [Table Text Block] Total current assets Assets, Current Stock Based Compensation Share-based Payment Arrangement [Policy Text Block] Stock Options Share-based Payment Arrangement, Option [Member] Long-term Debt, Type [Domain] Research and Development Arrangement, Contract to Perform for Others, Type Research and Development Arrangement, Contract to Perform for Others, Type [Axis] Weighted average contractual term, Outstanding Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term First advance used to repay previous debt Proceeds From First Advance Used To Repay Previous Debt The amount of proceeds from first advance used to repay previous debt. Income Tax Expense (Benefit), Total Income tax benefit Income Tax Expense (Benefit) Earnings Per Share, Basic and Diluted, Total Net loss per common share, basic and diluted Earnings Per Share, Basic and Diluted Antidilutive Securities Antidilutive Securities [Axis] Loss Contingencies [Line Items] Loss Contingencies [Line Items] Accounting Policies [Table] Accounting Policies [Table] Accounting policies. Number of shares, Outstanding, beginning balance Number of shares, Outstanding, ending balance Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Number Outstanding principle and advances under the loans agreement exceeds 65 million Outstanding Advances Under Loan Agreement Equals Or Exceeds Sixty Five Million [Member] Represents the information if the outstanding principle and advances under loan agreement exceeds fifty five million. Aggregate intrinsic value, Vested and expected to vest Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value Common Stock, Shares, Outstanding, Ending Balance Common Stock, Shares, Outstanding, Beginning Balance Common stock, shares outstanding Common Stock, Shares, Outstanding Plan Name Plan Name [Axis] Number of shares, Forfeited Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures in Period Development milestones Development Milestones Development milestones. Total operating expenses Operating Expenses 2019 Shelf Registration Two Thousand Nineteen Shelf Registration [Member] Two thousand nineteen shelf registration. Number of warrants exercised Warrants Exercised In Period Number of warrants (or share units) exercised during the current period. Weighted average exercise price, Outstanding, beginning balance Weighted average exercise price, Outstanding, ending balance Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price Cash flows from operating activities Net Cash Provided by (Used in) Operating Activities [Abstract] Prepaid expenses and other current assets Increase Decrease In Prepaid Expense And Other Assets Current The increase (decrease) during the reporting period in the value of prepaid expenses and other current assets not separately disclosed in the statement of cash flows, for example, deferred expenses, intangible assets, or income taxes. Accounting Policies [Line Items] Accounting Policies [Line Items] Accounting policies. Schedule of Future Minimum Lease Payments of Operating Leases Lessee, Operating Lease, Liability, Maturity [Table Text Block] Exercise price of warrants (in dollars per share) Weighted average exercise price, Beginning balance Weighted average exercise price, Ending balance Class of Warrant or Right, Exercise Price of Warrants or Rights Earnings Per Share [Abstract] 2024 Lessee, Operating Lease, Liability, to be Paid, Year Two Net loss Net loss Net Income (Loss) Attributable to Parent 2015 Plan Two Thousand Fifteen Equity Compensation Plan [Member] Represents information pertaining to the 2015 Equity Compensation Plan. AXS-05 Axs05 [Member] Represents information pertaining to AXS-05. Concentration of Credit Risk Concentration Risk, Credit Risk, Policy [Policy Text Block] Operating lease, discount rate Operating Lease, Weighted Average Discount Rate, Percent Research and Development Research and Development Expense [Member] Document Fiscal Period Focus Document Fiscal Period Focus Tranche Three Sub Tranche Two Tranche Three Sub Tranche Two [Member] Tranche three sub tranche two. December 2019 Sales Agreement December Two Thousand Nineteen Sales Agreement [Member] December two thousand nineteen sales agreement. Accounting Policies [Abstract] Entity Address, Address Line One Entity Address, Address Line One Number of shares, Outstanding, beginning balance Number of shares, Outstanding, ending balance Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number Jazz Pharmaceuticals Plc Jazz Pharmaceuticals Plc [Member] Jazz pharmaceuticals Plc. Total current liabilities Liabilities, Current Cash pay interest multiplier Debt Instrument Cash Pay Interest Multiplier Represents the multiplier used for the cash pay interest under the debt instrument. Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total Net loss Net Income (Loss), Including Portion Attributable to Noncontrolling Interest Entity Address, Postal Zip Code Entity Address, Postal Zip Code Share price not less than three day volume weighted average share price discount rate Share price not less than three day volume weighted average share price discount rate. Add: accreted liability of final payment fee Debt Instrument Accreted Liability Of Final Payment Fee Amount of accreted liability of final payment fee. Aggregate intrinsic value, Outstanding Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Intrinsic Value Total lease payments Lessee, Operating Lease, Liability, to be Paid Product and Service Product and Service [Domain] Issuance of common stock upon exercise of warrants Stock Issued During Period Value Warrants Exercised Value of stock issued as a result of the exercise of warrants. Fair value share price Share Price Fair Value Fair value price of a single share of a number of saleable stocks of a company Collaborative Arrangement and Arrangement Other than Collaborative Collaborative Arrangement and Arrangement Other than Collaborative [Domain] Schedule Of Research And Development Arrangement Contract To Perform For Others [Table] Schedule of Research and Development Arrangement, Contract to Perform for Others [Table] Net cash used in operating activities Net Cash Provided by (Used in) Operating Activities Proceeds from issuance of common stock, net Stock Issued During Period Value New Issues Net Net equity impact of the value of new stock issued during the period. Includes shares issued in an initial public offering or a secondary public offering. Issuance of common stock upon vesting of RSUs Stock Vested During Period Value Restricted Common Stock Award Stock vested during period value restricted common stock award. Equity Components Equity Components [Axis] Schedule of Operating Lease Expense Lease, Cost [Table Text Block] Current assets: Assets, Current [Abstract] Tranche Two Sub-Tranche Two Tranche Two Sub Tranche Two [Member] Tranche two sub tranche two. Entity Registrant Name Entity Registrant Name Amortization of debt issuance costs Amortization of Debt Issuance Costs Stockholders' Equity Stockholders' Equity Note Disclosure [Text Block] Entity Interactive Data Current Entity Interactive Data Current Prime Rate Prime Rate [Member] Entity Address, City or Town Entity Address, City or Town 2022 Long-Term Debt, Maturity, Remainder of Fiscal Year Trading Symbol Trading Symbol Cash flows from investing activities Net Cash Provided by (Used in) Investing Activities [Abstract] Percentage of aggregate amount of loan Debt Instrument Aggregate Amount Percentage Percentage of aggregate amount of loan. Less imputed interest Lessee, Operating Lease, Liability, Undiscounted Excess Amount Percentage of final payment fee Debt Instrument Final Payment Fee Threshold Percentage Of Debt Outstanding The final payment fee to be paid under the debt arrangement as a percentage of aggregate amount of all term loan advances minus the aggregate amount of repayments made. Minimum product revenue percent Long Term Debt Additional Drawn Minimum Revenue Percent The minimum percentage of revenue should be achieved under the debt instrument. Local Phone Number Local Phone Number Total stockholders’ equity Beginning balance Ending balance Stockholders' Equity Attributable to Parent Weighted average exercise price Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract] Research and Development [Abstract] Preferred Stock, Shares Issued, Total Preferred stock, shares issued Preferred Stock, Shares Issued Statistical Measurement Statistical Measurement [Axis] Entity Small Business Entity Small Business Preferred Stock, Shares Outstanding, Ending Balance Preferred Stock, Shares Outstanding, Beginning Balance Preferred stock, shares outstanding Preferred Stock, Shares Outstanding Organization, Consolidation and Presentation of Financial Statements [Abstract] Leases Lessee, Leases [Policy Text Block] Share price Share Price Share Price Interest expense Interest Expense, Debt, Excluding Amortization APIC, Share-based Payment Arrangement, Increase for Cost Recognition, Total Stock-based compensation APIC, Share-based Payment Arrangement, Increase for Cost Recognition Credit Facility [Axis] Loan payable, long-term Loan payable, long-term Long-term Debt, Excluding Current Maturities Variable Rate Variable Rate [Axis] Issuance of common stock upon vesting of RSUs (in shares) Stock Vested During Period Shares Restricted Common Stock Award Stock vested during period shares restricted common stock award. Common stock, voting right per share Equity Instrument Voting Rights Per Share Represents the number of votes per share each holder of shares is entitled to. Variable Rate Variable Rate [Domain] Estimated useful life Property, Plant and Equipment, Useful Life Business Acquisition [Axis] Minimum percentage of cash to be maintained as a security Long Term Debt Additional Drawn Covenant Minimum Cash To Be Maintained As Security Percent The minimum percentage of cash to be maintained under debt instruments. Number of warrants outstanding beginning balance Number of warrants outstanding ending balance Class of Warrant or Right, Outstanding Tranche One Tranche One [Member] Tranche one. Weighted average exercise price, Granted Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Sale of Stock Sale of Stock [Domain] Equity [Abstract] Weighted average exercise price, Expired Share-based Compensation Arrangements by Share-based Payment Award, Options, Expirations in Period, Weighted Average Exercise Price Less: current portion of long-term debt Long Term Debt Current Net Of Noncurrent Debt Discount Amount, after noncurrent portion of unamortized (discount) premium and debt issuance costs, of long-term debt. Includes, but not limited to, notes payable, bonds payable, debentures, mortgage loans and commercial paper. Excludes capital lease obligations. Plan Name Plan Name [Domain] Thereafter Lessee Operating Lease Liability Payments Due After Year Four Lessee operating lease liability payments due after year four. Lender Name [Axis] 2023 Long-Term Debt, Maturity, Year One Depreciation, Total Depreciation Depreciation Lease term Lessee, Operating Lease, Term of Contract Upfront cash payment Initial Cash Payment Per Collaboration Agreement Initial Cash Payment Per Collaboration Agreement. License agreement royalty, maximum reduction percent as a result of required third party payments License Agreement Royalty Due Maximum Reduction Percentage As Result Of Required Payments To Third Parties Represents the maximum reduction percentage of the royalty due as a result of required payments to third parties. Proceeds from issuance of common stock, gross Stock Issued During Period, Value, New Issues Exercised (in dollars per share) Warrants Exercised In Period Weighted Average Exercise Price Weighted average price at which warrants were exercised. Cash Equivalents, at Carrying Value, Total Cash Equivalents Cash Equivalents, at Carrying Value Share-based Payment Arrangement, Noncash Expense, Total Stock-based compensation expense Share-based Payment Arrangement, Noncash Expense Prepaid and other current assets Prepaid Expense and Other Assets, Current Term of warrants (in years) Class Of Warrant Or Right Term Period during which warrants are active, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days. Summary of Stock Option Activity Share-based Payment Arrangement, Option, Activity [Table Text Block] Total principal payments outstanding Total Outstanding Debt Long-term Debt, Gross Number of shares, Exercisable Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Number Net cash (used in) provided by financing activities Net Cash Provided by (Used in) Financing Activities Shares tendered for withholding taxes Adjustments To Additional Paid In Capital Shares Tendered For Withholding Taxes Adjustments to Additional paid-in capital Shares tendered for withholding taxes. Commitments and Contingencies Disclosure [Abstract] Operating lease right-of-use asset obtained in exchange for operating lease liability Right-of-Use Asset Obtained in Exchange for Operating Lease Liability Debt instrument, interest payment period Debt Instrument Interest Payment Period Debt instrument, interest payment period. Interest income (expense) Investment Income, Net, Total Investment Income, Net Weighted average grant date fair value, Vested Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value Total assets Assets Number of shares, Exercised Issuance of common stock upon exercise of options (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period Statement [Line Items] Statement [Line Items] Total liabilities and stockholders’ equity Liabilities and Equity Document Quarterly Report Document Quarterly Report Equipment Property, Plant and Equipment [Abstract] Statement of Cash Flows [Abstract] Additional Paid-in Capital Additional Paid-in Capital [Member] Term loan 2020 tranche three Term Loan2020 Tranche Three [Member] Represents about term loan tranche three. Title of 12(b) Security Title of 12(b) Security Line of credit Long-term Line of Credit Long-term Line of Credit, Total December 2019 and March 2022 Sales Agreement December Two Thousand Nineteen and March Two Thousand Twenty Two Sales Agreement [Member] December two thousand nineteen and march two thousand twenty two sales agreement. Debt Instrument [Line Items] Debt Instrument Prepayment Occurs On Or After First Anniversary And Prior To Second Anniversary Of First Amendment Closing Date [Member] Debt instrument prepayment occurs on or after first anniversary and prior to second anniversary of first amendment closing date. Prepayment Occurs on or After First Anniversary and Prior to Second Anniversary of First Amendment Closing Date Second Amendment To Loan and Security Agreement Second Amendment To Loan and Security Agreement [Member] Second amendment to loan and security agreement. Award Type Award Type [Domain] Schedule of Principal Payments Schedule of Maturities of Long-term Debt [Table Text Block] Research and Development Arrangement, Contract to Perform for Others, Type Research and Development Arrangement, Contract to Perform for Others, Type [Domain] Base interest rate Debt Instrument, Interest Rate, Stated Percentage Term Loan2020 [Member] Represents about term loan two thousand twenty. Term Loan 2020 Weighted average exercise price, Vested and expected to vest Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price Number of shares, Granted Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross Entity Current Reporting Status Entity Current Reporting Status Scenario Scenario [Domain] Investment, Name Investment, Name [Domain] Weighted average grant date fair value, Granted Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value Less: unamortized debt discount, long-term Debt Instrument, Unamortized Discount, Noncurrent Lessee, operating lease, option to extend Basic and Diluted Net Loss per Common Share Earnings Per Share, Policy [Policy Text Block] Number of exclusive license agreements Number Of License Agreements Represents the number of license agreements the Company has entered into. Schedule of Stock-Based Compensation Expense Recognized Share-based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block] 2022 Lessee, Operating Lease, Liability, to be Paid, Remainder of Fiscal Year Proceeds from debt Proceeds from Issuance of Debt Accrued Liabilities and Other Liabilities [Abstract] Long-term Debt, Type [Axis] Period to achieve first milestone Threshold Days To Achieve First Milestone Number of days to achieve first milestone following such date. Income Statement Location Income Statement Location [Domain] License agreement royalty as a percent of net sales License Agreement Royalty Due Percentage Of Net Sales Represents the percentage of net sales of products containing the licensed products, due to licensor as a royalty. Preferred stock, shares authorized Preferred Stock, Shares Authorized Weighted average exercise price, Exercisable Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Exercise Price Minimum Minimum Issuance of common stock upon financing (in shares) Stock Issued During Period Shares Financing Number of shares of stock issued during the period pursuant to a financing arrangement. Weighted average contractual term, Vested and expected to vest Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term Issuance of common stock upon exercise of options Stock Issued During Period, Value, Stock Options Exercised AXS-04 Axs04 [Member] Represents information pertaining to AXS-04. Number of shares, Granted Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Grants in Period AXS-05 and AXS-07 Axs05 And Axs07 [Member] Represents the information pertaining to AXS-05 and AXS-07. Common stock to be issued if warrants are exercised (in shares) Class of Warrant or Right, Number of Securities Called by Warrants or Rights Lessee, Operating Lease, Liability, Payment, Due [Abstract] Nature of Business and Basis of Presentation Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block] Cash flows from financing activities Net Cash Provided by (Used in) Financing Activities [Abstract] Debt Instrument Debt Instrument [Axis] Foreign Currency Translation Foreign Currency Transactions and Translations Policy [Policy Text Block] Entity Filer Category Entity Filer Category Income Taxes Income Tax, Policy [Policy Text Block] Trading days Class Of Warrants Or Rights Weighted Average Price Trading Days Threshold period of specified consecutive trading days within which the volume weighted average price of company's common stock. Document Fiscal Year Focus Document Fiscal Year Focus Sunosi Sunosi [Member] Sunosi. Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Number of shares, Vested and expected to vest Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table] Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table] Accrued Interest Interest Payable, Current Weighted average grant date fair value Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value Retained Earnings (Accumulated Deficit), Ending Balance Retained Earnings (Accumulated Deficit), Beginning Balance Retained Earnings (Accumulated Deficit), Total Accumulated deficit Accumulated deficit Retained Earnings (Accumulated Deficit) Share-based Compensation Arrangement by Share-based Payment Award, Options, Nonvested, Number of Shares, Ending Balance Share-based Compensation Arrangement by Share-based Payment Award, Options, Nonvested, Number of Shares, Beginning Balance Non-vested options outstanding Share-based Compensation Arrangement by Share-based Payment Award, Options, Nonvested, Number of Shares Maximum Maximum Entity Central Index Key Entity Central Index Key Business Acquisition, Acquiree [Domain] Cash Equivalents Cash and Cash Equivalents, Policy [Policy Text Block] Entity Tax Identification Number Entity Tax Identification Number Equity Component Equity Component [Domain] Minimum percentage of cash to be maintained as a security following market capitalization condition Long Term Debt Additional Drawn Covenant Minimum Cash To Be Maintained As Security With Market Capitalization Covenant Percent The minimum percentage of cash to be maintained as security following the market capitalization conditions under the debt instruments. Preferred stock, par value Preferred Stock, Par or Stated Value Per Share Loss on extinguishment of debt Loss on extinguishment of debt Gain (Loss) on Extinguishment of Debt Gain (Loss) on Extinguishment of Debt, Total Equipment Property, Plant and Equipment, Policy [Policy Text Block] Recent Accounting Pronouncements Accounting Standards Update and Change in Accounting Principle [Abstract] Expected vesting period for non-vested share-based compensation Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition Cash Equivalents Cash Equivalents, at Carrying Value [Abstract] Loan and Security Agreement Long-term Debt [Text Block] Change in accounting principle, accounting standards update, adoption date Change in Accounting Principle, Accounting Standards Update, Adoption Date Subsequent Events [Abstract] Statement [Table] Statement [Table] Operating lease, remaining lease term Operating Lease, Weighted Average Remaining Lease Term Outstanding principle and advances under the loans agreement exceeds 55 million Outstanding Advances Under Loan Agreement Equals Or Exceeds Fifty Five Million [Member] Represents the information if the outstanding principle and advances under loan agreement exceeds fifty five million. Entity File Number Entity File Number Share Based Compensation Arrangement By Share Based Payment Award [Line Items] Share-based Compensation Arrangement by Share-based Payment Award [Line Items] Segment and Geographic Information Segment Reporting, Disclosure of Entity's Reportable Segments [Abstract] Accumulated Deficit Retained Earnings [Member] Adjustments to reconcile net loss to net cash used in operating activities: Adjustments, Noncash Items, to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Accounting Standards Update Accounting Standards Update [Domain] Accounting Standards Update Accounting Standards Update [Axis] Increase (Decrease) in Accounts Payable, Total Accounts payable Increase (Decrease) in Accounts Payable Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items] Share-based Payment Arrangement, Expensed and Capitalized, Amount [Line Items] Underwritten Public Offering Underwritten Public Offering [Member] An underwritten sale of stock. Current liabilities: Liabilities, Current [Abstract] Upfront payment Upfront Payment Upfront payment. Basic and diluted net loss per common share: Earnings Per Share, Basic and Diluted [Abstract] Commitments and Contingencies Commitments and Contingencies Disclosure [Text Block] Aggregate intrinsic value, Exercisable Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Exercisable, Aggregate Intrinsic Value Operating Lease, Liability, Total Present value of operating lease liabilities Operating Lease, Liability Common Stock Common Stock [Member] Cover [Abstract] Credit Facility [Domain] Weighted average grant date fair value, Outstanding, beginning balance Weighted average grant date fair value, Outstanding, ending balance Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value Prepayment Occurs on or After First Anniversary and Prior to Second Anniversary of the Closing Date Debt Instrument Prepayment Occurs On Or After First Anniversary And Prior To Second Anniversary Of Closing Date [Member] Represents the prepayment of debt occurring on or after the first anniversary and prior to the second anniversary of the Closing Date. Statement of Stockholders' Equity [Abstract] Number of operating segments Number of Operating Segments Accrued expenses and other current liabilities Increase (Decrease) in Other Accounts Payable and Accrued Liabilities Fair Value of Financial Instruments Fair Value of Financial Instruments, Policy [Policy Text Block] Change in operating lease liability Change In Operating Lease Liability Change in operating lease liability. Research And Development Arrangement Contract To Perform For Others [Line Items] Research and Development Arrangement, Contract to Perform for Others [Line Items] Restricted Stock Units Restricted Stock Units (RSUs) [Member] Document Transition Report Document Transition Report Term loan 2020 tranche five Term Loan2020 Tranche Five [Member] Represents about term loan tranche five. Significant Risks And Uncertainties Significant Risks And Uncertainties Policy Policy [Text Block] Disclosure of accounting policy for significant risks and uncertainties. Proceeds from issuance of common stock upon exercise of options Proceeds from Stock Options Exercised Research and Development Expense, Total Research and development expense recognized Research and development Research and Development Expense Stock-based compensation expense Share-based Payment Arrangement, Expense Warrants Issued During Period Debt Financing Warrants issued during period debt financing. Issuance of warrants upon debt financing 2020-10 Accounting Standards Update 2020-10 [Member] Number of warrants issued Warrants Issued In Period Number of warrants (or share units) issued during the current period. Statement of Financial Position [Abstract] Number of shares, Vested Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Vested in Period Amortization of operating lease right-of-use asset Prior trading days Consecutive Trading Days Represents the consecutive number of trading days to determine the weighted average price per share of ordinary shares. Stockholders’ equity: Stockholders' Equity Attributable to Parent [Abstract] Weighted average contractual term Share-based Compensation Arrangement by Share-based Payment Award, Options, Additional Disclosures [Abstract] License agreement term, from first commercial sale License Agreement Term Period of time, after the first commercial sale of the applicable product, the license agreement is valid, in PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days. Warrants and Rights Note Disclosure [Abstract] Computation of Basic and Diluted Net Loss per Common Share Schedule of Earnings Per Share, Basic and Diluted [Table Text Block] Weighted average exercise price, Exercised Share-based Compensation Arrangements by Share-based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price 2026 Long-Term Debt, Maturity, Year Four Changes in operating assets and liabilities: Increase (Decrease) in Operating Capital [Abstract] 2025 Lessee, Operating Lease, Liability, to be Paid, Year Three Hercules Capital Inc Hercules Capital Inc [Member] Hercules Capital Inc. Entity Common Stock, Shares Outstanding Entity Common Stock, Shares Outstanding Prepayment Occurs on or After Second Anniversary and Prior to Third Anniversary of Closing Date Debt Instrument Prepayment Occurs On Or After Second Anniversary And Prior To Third Anniversary Of Closing Date [Member] Represents the prepayment of debt occurring after the second anniversary and prior to the third anniversary of the Closing Date. Award Type Award Type [Axis] Entity Shell Company Entity Shell Company Liabilities and stockholders’ equity Liabilities and Equity [Abstract] Entity Incorporation, State or Country Code Entity Incorporation, State or Country Code Net Loss per Common Share Earnings Per Share [Text Block] Term loan 2020 tranche four Term Loan2020 Tranche Four [Member] Represents about term loan tranche four. Counterparty Name Counterparty Name [Domain] March 2022 Sales Agreement March Two Thousand Twenty Two Sales Agreement [Member] March Two Thousand Twenty Two Sales Agreement [Member] Percentage of prepayment penalty Debt Instrument Prepayment Penalty Percentage Represents the prepayment penalty percentage on principal amount of debt. Minimum cash to be maintain as a first priority security interest Long Term Debt Additional Drawn Covenant Minimum Cash As Security Interest The minimum amount of cash should be maintained as first priority security interest under the terms of debt instrument. Number of shares Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward] Amendment Flag Amendment Flag Product and Service Product and Service [Axis] Term Loan Term Loan [Member] Term loan. Cash and Cash Equivalents, at Carrying Value, Ending Balance Cash and Cash Equivalents, at Carrying Value, Beginning Balance Cash and Cash Equivalents, at Carrying Value, Total Cash and cash equivalents Cash and Cash Equivalents, at Carrying Value Recent Accounting Pronouncements New Accounting Pronouncements, Policy [Policy Text Block] Tranche Two Sub-Tranche Three Tranche Two Sub Tranche Three [Member] Tranche two sub tranche three. 2019 Term Loan Term Loan2019 [Member] This member stands for Term Loan 2019. Unrecognized compensation cost related to non-vested stock options expected to be recognized Share-based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount Long-term Debt, Total Outstanding amount Long-term Debt Subsequent Event Subsequent Events [Text Block] Amortization of debt discount Amortization of Debt Discount (Premium) Antidilutive Securities, Name Antidilutive Securities, Name [Domain] Other Assets, Noncurrent, Total Other assets Other Assets, Noncurrent Collaborative Arrangement and Arrangement Other than Collaborative Collaborative Arrangement and Arrangement Other than Collaborative [Axis] Sale of Stock Sale of Stock [Axis] Issuance of common stock upon exercise of warrants (in shares) Stock Issued During Period Shares Stock Warrants Exercised Number of shares of stock issued as a result of the exercise of warrants. Line Of Credit Facility [Table] Line of Credit Facility [Table] Compensation cost not yet recognized related to unvested RSUs Share-based Payment Arrangement, Nonvested Award, Excluding Option, Cost Not yet Recognized, Amount Proceeds from issuance of common stock upon financing, net Proceeds from Issuance of Common Stock